Glycogen‐rich tumor of the oral minor salivary glands a histochemical and ultrastructural study

A detailed electronmicroscopic study on glycogen‐rich tumor is presented. The neoplasm originated from the minor salivary glands on the ventral surface of the tongue. The role of myoepithelial cells in the histogenesis of this lesion is not supported. It is proposed that the tumor arises from “undif...

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Bibliographic Details
Published in:Cancer 1983-07, Vol.52 (1), p.105-111
Main Authors: Chaudhry, Anand P., Cutler, Leslie S., Satchidanand, Sateesh, Labay, Gerald, Raj, Mary Sunder, Lin, Cheng‐Chung
Format: Article
Language:English
Subjects:
Adenoma - analysis
Glycogen - analysis
Histocytochemistry
Humans
Male
Microscopy, Electron
Middle Aged
Salivary Gland Neoplasms - analysis
Salivary Gland Neoplasms - ultrastructure
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Summary:A detailed electronmicroscopic study on glycogen‐rich tumor is presented. The neoplasm originated from the minor salivary glands on the ventral surface of the tongue. The role of myoepithelial cells in the histogenesis of this lesion is not supported. It is proposed that the tumor arises from “undifferentiated” stem cells analogous to cells in the “end bud” stage of salivary gland morphogenesis. The presence of a large amount of glycogen is secondary to defective carbohydrate metabolism within the tumor cells. Cancer 52:105‐111, 1983.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19830701)52:1<105::AID-CNCR2820520120>3.0.CO;2-B