Interaction of ethidium bromide with yeast cells investigated by electron probe X-ray microanalysis

K super(+) efflux provoked by ethidium proceeds partially as an all-or-none effect by which the diffusion barrier for K super(+) is disrupted and partially from still intact cells, presumably by exchange against ethidium. Thisis shown by the application of an electron probe microanalysis X-ray techn...

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Bibliographic Details
Published in:The Journal of membrane biology 1983-01, Vol.73 (2), p.131-136
Main Authors: Theuvenet, A P, Bindels, R J, van Amelsvoort, J M, Borst-Pauwels, G W, Stols, A L
Format: Article
Language:English
Subjects:
Calcium - metabolism
Cell Membrane Permeability - drug effects
Cell Survival - drug effects
electron microprobe
Electron Probe Microanalysis
Ethidium - pharmacology
ethidium bromide
Phosphorus - metabolism
potassium
Potassium - metabolism
Saccharomyces cerevisiae
Saccharomyces cerevisiae - drug effects
Saccharomyces cerevisiae - metabolism
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Summary:K super(+) efflux provoked by ethidium proceeds partially as an all-or-none effect by which the diffusion barrier for K super(+) is disrupted and partially from still intact cells, presumably by exchange against ethidium. Thisis shown by the application of an electron probe microanalysis X-ray technique by which the K super(+) content of individual cells is analyzed.
ISSN:0022-2631
1432-1424
DOI:10.1007/BF01870436