EFFECTS OF PAROMOMYCIN SULFATE ON DIPHYLLOBOTHRIUM LATUM INFECTIONS

About 50 mg/kg of paromomycin sulfate was administered orally in a single or 2 divided doses to patients with Diphyllobothrium latum infections. The following results were obtained. 1. After the treatment with paromomycin sulfate mature strobilae were expelled in all of 7 patients with Diphyllobothr...

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Bibliographic Details
Published in:Japanese journal of antibiotics 1983/03/25, Vol.36(3), pp.615-618
Main Authors: NAGASE, KIYOSHI, SAITO, MASAO, MIYAZAKI, TAMOTSU, YOKOTA, SHINICHI, KOBAYASHI, MASANOBU, SASAKI, CHIHIRO, UEHATA, YASUSHI, ASAKA, MASAHIRO
Format: Article
Language:Japanese
Subjects:
Adult
Diphyllobothriasis - drug therapy
Drug Evaluation
Female
Humans
Japan
Male
Paromomycin - administration & dosage
Paromomycin - adverse effects
Paromomycin - therapeutic use
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Summary:About 50 mg/kg of paromomycin sulfate was administered orally in a single or 2 divided doses to patients with Diphyllobothrium latum infections. The following results were obtained. 1. After the treatment with paromomycin sulfate mature strobilae were expelled in all of 7 patients with Diphyllobothrium latum infections. 2. We couldn't find scolices in all cases. 3. Although these stools were examined for 2 months after the treatment, the eggs of Diphyllobothrium latum were not identified. 4. No side effects were observed in all cases. It was concluded that paromomycin sulfate was effective on the treatment of Diphyllobothrium latum infections.
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.36.615