Pyoderma Gangrenosum with Cutaneous T-Cell Lymphoma Manifested as Lower Extremity Ulcers—Case Reports

Patients with extensive lower extremity ulcerations initially thought to be vascular disease were subsequently proved to have pyoderma gangrenosum and malignant lymphoma. Both patients died of sepsis; one patient exhibited hypogammaglobulinemia involving immunoglobulins IgA, IgG, and IgE; in the sec...

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Bibliographic Details
Published in:Angiology 1991-06, Vol.42 (6), p.498-503
Main Authors: Kitahama, Akio, Roland, Phillip Y., Kerstein, Morris D.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Female
Hematologic and hematopoietic diseases
Humans
Immunoglobulins - metabolism
Leg Ulcer - etiology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphoma, T-Cell, Cutaneous - complications
Lymphoma, T-Cell, Cutaneous - immunology
Medical sciences
Pyoderma - complications
Skin Neoplasms - complications
Skin Neoplasms - immunology
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Description
Summary:Patients with extensive lower extremity ulcerations initially thought to be vascular disease were subsequently proved to have pyoderma gangrenosum and malignant lymphoma. Both patients died of sepsis; one patient exhibited hypogammaglobulinemia involving immunoglobulins IgA, IgG, and IgE; in the second patient, a polyclonal excess involving IgA and IgE was present.
ISSN:0003-3197
1940-1574
DOI:10.1177/000331979104200610