ASSESSMENT OF THE ALLERGENIC POTENTIAL OF ALTHESIN AND ITS CONSTITUENTS

The pharmaceutical formulation of Althesin was shown to have a weak allergenic potential in the guineapig maximization test. Alphadolone and alphaxalone acetate were found to be devoid of such potential, while the status of Cremophor EL remained equivocal.

Saved in:
Bibliographic Details
Published in:British journal of anaesthesia : BJA 1983-08, Vol.55 (8), p.715-717
Main Authors: TACHON, P., DESCOTES, J., LASCHI-LOQUERIE, A., GUILLOT, J.P., EVREUX, J.C.
Format: Article
Language:English
Subjects:
Alfaxalone Alfadolone Mixture - immunology
Anesthetics - immunology
Animals
Drug Hypersensitivity - immunology
Female
Glycerol - analogs & derivatives
Glycerol - immunology
Guinea Pigs
Intradermal Tests
Male
Pregnanediones - immunology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The pharmaceutical formulation of Althesin was shown to have a weak allergenic potential in the guineapig maximization test. Alphadolone and alphaxalone acetate were found to be devoid of such potential, while the status of Cremophor EL remained equivocal.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/55.8.715