Late relapse from complete remission in nodular and diffuse histiocytic lymphoma

Twelve patients with unfavorable prognosis lymphomas (diffuse histiocytic lymphoma, 11; nodular histiocytic lymphoma, 1) treated predominantly with radiation therapy, are described in whom relapse of disease occurred late (>2.5 years, 2.8–26 years; median, 6.25 years) after achieving a complete r...

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Bibliographic Details
Published in:Cancer 1983-10, Vol.52 (8), p.1356-1359
Main Authors: Mead, Graham M., MacKintosh, F. Roy, Burke, Jerome S., Rosenberg, Saul A.
Format: Article
Language:English
Subjects:
Adult
Aged
Female
Follow-Up Studies
Humans
Lymphoma - pathology
Lymphoma - radiotherapy
Male
Middle Aged
Recurrence
Time Factors
Online Access:Get full text
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Description
Summary:Twelve patients with unfavorable prognosis lymphomas (diffuse histiocytic lymphoma, 11; nodular histiocytic lymphoma, 1) treated predominantly with radiation therapy, are described in whom relapse of disease occurred late (>2.5 years, 2.8–26 years; median, 6.25 years) after achieving a complete remission. Although relapse probably represented regrowth of clinically quiescent tumor, it is also possible that these were second malignancies, perhaps occurring in a predisposed host. Continued long‐term analysis of clinical trials is important to document this uncommon occurrence.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19831015)52:8<1356::AID-CNCR2820520803>3.0.CO;2-M