Redetermination of the rate-limiting step in the activation of factor IX by factor XIa and by factor VIIa/tissue factor. Explanation for different electrophoretic radioactivity profiles obtained on activation of 3H- and 125I-labeled factor IX

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Bibliographic Details
Published in:Biochemistry (Easton) 1983-08, Vol.22 (17), p.4047-4053
Main Authors: Bajaj, S. Paul, Rapaport, Samuel I, Russell, William A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood coagulation. Blood cells
Brain - metabolism
Coagulation factors
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Factor IX - metabolism
Factor VII - metabolism
Factor VIIa
Factor XI - metabolism
Factor XIa
Fundamental and applied biological sciences. Psychology
Humans
Iodine Radioisotopes
Kinetics
Macromolecular Substances
Molecular and cellular biology
Thromboplastin - metabolism
Tritium
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ISSN:0006-2960
1520-4995
DOI:10.1021/bi00286a009