3-Alkyl-4-aminobutyric acids: the first class of anticonvulsant agents that activates L-glutamic acid decarboxylase

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Bibliographic Details
Published in:Journal of medicinal chemistry 1991-07, Vol.34 (7), p.2295-2298
Main Authors: Silverman, Richard B, Andruszkiewicz, Ryszard, Nanavati, Shrenik M, Taylor, Charles P, Vartanian, Mark G
Format: Article
Language:English
Subjects:
Aliphatic compounds
Aminobutyrates - pharmacology
Animals
Anticonvulsants - pharmacology
Chemistry
Enzyme Activation - drug effects
Exact sciences and technology
Glutamate Decarboxylase - drug effects
Mice
Organic chemistry
Preparations and properties
Seizures - prevention & control
Stereoisomerism
Structure-Activity Relationship
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm00111a053