The skeletal manifestations of brucellosis

A prospective study of 33 patients with skeletal complications of brucellosis is reported. The diagnosis depends on the brucellar agglutination titre because the clinical, radiological and histological features are not specific, and blood culture and culture of synovial fluid are often negative. The...

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Bibliographic Details
Published in:International orthopaedics 1991-01, Vol.15 (1), p.17-19
Main Authors: SANKARAN-KUTTY, M, MARWAH, S, KANNAN KUTTY, M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anti-Bacterial Agents
Arthritis, Infectious - diagnostic imaging
Arthritis, Infectious - etiology
Bacterial arthritis and osteitis
Bacterial diseases
Biological and medical sciences
Brucellosis - complications
Brucellosis - diagnosis
Brucellosis - drug therapy
Child
Drug Therapy, Combination - therapeutic use
Female
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Prospective Studies
Radiography
Rifampin - administration & dosage
Sacroiliac Joint
Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage
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Summary:A prospective study of 33 patients with skeletal complications of brucellosis is reported. The diagnosis depends on the brucellar agglutination titre because the clinical, radiological and histological features are not specific, and blood culture and culture of synovial fluid are often negative. The commonest site is the sacroiliac joint, and brucellosis must be differentiated from tuberculosis as an important cause of backache. Treatment is with chemotherapy, the preferred combination being rifampicin and co-trimoxazole. Relapse can occur, but the chances can be reduced by careful clinical monitoring, and by repeated serological tests and gallium scanning; it is treated by further chemotherapy. Operation is indicated to relieve spinal cord compression or to drain a large paravertebral abscess.
ISSN:0341-2695
1432-5195
DOI:10.1007/BF00210526