Collagenous colitis with involvement of terminal ileum

We present a case of collagenous colitis with evidence of terminal ileal involvement. The patient suffered from chronic watery diarrhea of three months' duration, and colonoscopy revealed a normal endoscopic appearance. Histologic examination of biopsies revealed a broad subepithelial band of c...

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Bibliographic Details
Published in:Digestive diseases and sciences 1991-08, Vol.36 (8), p.1161-1163
Main Authors: LEWIS, F. W, WARREN, G. H, GOFF, J. S
Format: Article
Language:English
Subjects:
Biological and medical sciences
Colitis - complications
Colitis - pathology
Collagen - analysis
Colon - pathology
Diarrhea - etiology
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Ileitis - complications
Ileitis - pathology
Ileum - pathology
Intestinal Mucosa - pathology
Medical sciences
Middle Aged
Other diseases. Semiology
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Summary:We present a case of collagenous colitis with evidence of terminal ileal involvement. The patient suffered from chronic watery diarrhea of three months' duration, and colonoscopy revealed a normal endoscopic appearance. Histologic examination of biopsies revealed a broad subepithelial band of collagen, with similar histologic findings in the terminal ileum. Additionally, the patient exhibited abnormalities of d-xylose and vitamin B12 absorption, although there were no clinical signs of malabsorption. Biopsy of the proximal small intestine was normal. The significance of these findings for the definition of the clinicopathologic entity of collagenous colitis and its pathogenesis are discussed.
ISSN:0163-2116
1573-2568
DOI:10.1007/bf01297466