Bone Marrow Involvement in a Patient with Paracoccidioidomycosis: A Rare Presentation of Juvenile Form

Paracoccidioides brasiliensis rarely shows bone marrow involvement and its response to treatment with itraconazole in children needs further assessment. We describe here a child with a juvenile disseminated form of paracoccidioidomycosis, which showed reticuloendothelial system involvement and the p...

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Bibliographic Details
Published in:Mycopathologia (1975) 2010-10, Vol.170 (4), p.259-261
Main Authors: Pereira, Graziella Hanna, Santos, Aline Queiroz, Park, Miriam, Muller, Patricia Rady, Padua, Soraia, Marchesi, Raquel Ferrari, Aldred, Vera Lucia
Format: Article
Language:English
Subjects:
Antifungal Agents - therapeutic use
Biomedical and Life Sciences
Biopsy
bone marrow
Bone Marrow - microbiology
Bone Marrow - pathology
Child
Endemic mycosis
Eukaryotic Microbiology
Female
Histocytochemistry
Humans
Itraconazole
Itraconazole - therapeutic use
Life Sciences
Lymph Nodes - pathology
Medical Microbiology
Microbial Ecology
Microbiology
Microscopy
Osteomyelitis - diagnosis
Osteomyelitis - drug therapy
Osteomyelitis - microbiology
Osteomyelitis - pathology
Paracoccidioides - isolation & purification
Paracoccidioides brasiliensis
Paracoccidioidomycosis
Paracoccidioidomycosis - complications
Paracoccidioidomycosis - drug therapy
Plant Sciences
Treatment Outcome
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Summary:Paracoccidioides brasiliensis rarely shows bone marrow involvement and its response to treatment with itraconazole in children needs further assessment. We describe here a child with a juvenile disseminated form of paracoccidioidomycosis, which showed reticuloendothelial system involvement and the presence of Paracoccidioides brasiliensis in the bone marrow. The patient showed an effective and rapid response to itraconazole therapy.
ISSN:0301-486X
1573-0832
DOI:10.1007/s11046-010-9314-5