The sensitivity ofEscherichia coli strains with K1 surface antigen and rods without this antigen to the bactericidal effect of serum

The susceptibility ofEscherichia coli strains with K1 surface antigen (K1+) and rods without this antigen (K1−) to the bactericidal action of normal bovine serum and human normal cord serum was determined. SeventyE. coli strains (35 K1+ and 35 K1−) were isolated from urine obtained from children wit...

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Bibliographic Details
Published in:Folia microbiologica 2004-07, Vol.49 (4), p.471-478
Main Authors: Cisowska, A, Jankowski, S
Format: Article
Language:English
Subjects:
Antigens
Bacteria
Cells
Complement activation
E coli
Rods
Sensitivity
Urinary tract
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Summary:The susceptibility ofEscherichia coli strains with K1 surface antigen (K1+) and rods without this antigen (K1−) to the bactericidal action of normal bovine serum and human normal cord serum was determined. SeventyE. coli strains (35 K1+ and 35 K1−) were isolated from urine obtained from children with urinary tract infections. The strains investigated showed variable sensitivity to the bactericidal action of the sera.E. coli K1+ strains were characterized by lower sensitivity to bactericidal effect of the sera in comparison with K1− rods. The role of the particular mechanisms of complement activation in the process of killing of theE. coli strains was also determined.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF02931611