In Vitro Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

• Published in: Journal of Virology 2010-11, Vol.84 (22), p.11961-11969
• Main Authors: KOH, Yasuhiro, AMANO, Masayuki, TOWATA, Tomomi, DANISH, Matthew, LESHCHENKO-YASHCHUK, Sofiya, DAS, Debananda, NAKAYAMA, Maki, TOJO, Yasushi, GHOSH, Arun K, MITSUYA, Hiroaki
• Format: Article
• Language: English
• Subjects: Amino Acid Sequence; Animals; Biological and medical sciences; Cell Line; Cercopithecus aethiops; COS Cells; Drug Resistance, Viral; Fundamental and applied biological sciences. Psychology; HIV Infections - drug therapy; HIV Infections - virology; HIV Protease Inhibitors - pharmacology; HIV-1 - drug effects; HIV-1 - genetics; HIV-1 - isolation & purification; HIV-1 - physiology; Human immunodeficiency virus 1; Humans; Microbiology; Miscellaneous; Molecular Sequence Data; Mutation; Ritonavir - pharmacology; Sequence Alignment; Vaccines and Antiviral Agents; Viral Proteins - chemistry; Viral Proteins - genetics; Virology; Virus Replication - drug effects
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.00967-10

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