Stimulation of Proliferation of 19S Antibody-forming Cells in the Spleens of Immunized Guinea-pigs after Exchange Transfusion

THERE is abundant evidence that the immune response, both primary (19S) and secondary (7S), is regulated by a feed-back mechanism involving serum antibody, particularly 7S antibody 1–4 , but the exact mechanism remains unclear.

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Bibliographic Details
Published in:Nature (London) 1970-12, Vol.228 (5278), p.1304-1305
Main Authors: STURGILL, BENJAMIN C., WORZNIAK, MICHAEL J.
Format: Article
Language:English
Subjects:
Alpha-Globulins
Animals
Antibodies - analysis
Antibody Formation
Antibody-Producing Cells - cytology
Erythrocytes - immunology
Exchange Transfusion, Whole Blood
Feedback
Guinea Pigs
Humanities and Social Sciences
Immunization
Immunoglobulin M - biosynthesis
letter
multidisciplinary
Science
Science (multidisciplinary)
Sheep
Spleen - cytology
Spleen - immunology
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Description
Summary:THERE is abundant evidence that the immune response, both primary (19S) and secondary (7S), is regulated by a feed-back mechanism involving serum antibody, particularly 7S antibody 1–4 , but the exact mechanism remains unclear.
ISSN:0028-0836
1476-4687
DOI:10.1038/2281304a0