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Early intervention, time-limited, targeted pharmacotherapy of schizophrenia

A growing appreciation of the risks of long-term, continuous neuroleptic use in the aftercare of schizophrenic patients has led to a search for alternative strategies. The authors report their experiences with the clinical strategy of "targeted" medication, in which patients are followed d...

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Published in:	Schizophrenia bulletin 1983, Vol.9 (4), p.533-542
Main Authors:	CARPENTER, W. T. JR, HEINRICHS, D. W
Format:	Article
Language:	English
Subjects:	Aftercare Antineoplastic agents Antipsychotic Agents - therapeutic use Biological and medical sciences Chemotherapy Drug Administration Schedule Drug Therapy Early Intervention Health Care Delivery Human Humans Maintenance Therapy Medical sciences Pharmacology. Drug treatments Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychosocial Rehabilitation Recurrence Schizophrenia Schizophrenia - drug therapy Schizophrenic Psychology
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container_title	Schizophrenia bulletin
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creator	CARPENTER, W. T. JR HEINRICHS, D. W
description	A growing appreciation of the risks of long-term, continuous neuroleptic use in the aftercare of schizophrenic patients has led to a search for alternative strategies. The authors report their experiences with the clinical strategy of "targeted" medication, in which patients are followed drug free until prodromal signs of impending relapse appear. Medication is then initiated to abort the impending episode and discontinued when patients restabilize clinically. Preliminary experience suggests that control of schizophrenic symptomatology comparable to that obtained with maintenance drugs can be achieved with a marked reduction in medication use when the targeted strategy is applied in the context of a broad-based program of psychosocial intervention based on a comprehensive medical model.
doi_str_mv	10.1093/schbul/9.4.533
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Psychiatry</topic><topic>Psychosocial Rehabilitation</topic><topic>Recurrence</topic><topic>Schizophrenia</topic><topic>Schizophrenia - drug therapy</topic><topic>Schizophrenic Psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CARPENTER, W. T. JR</creatorcontrib><creatorcontrib>HEINRICHS, D. W</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PsycARTICLES (ProQuest)</collection><collection>ProQuest One Psychology</collection><collection>MEDLINE - Academic</collection><jtitle>Schizophrenia bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CARPENTER, W. T. JR</au><au>HEINRICHS, D. 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subjects	Aftercare Antineoplastic agents Antipsychotic Agents - therapeutic use Biological and medical sciences Chemotherapy Drug Administration Schedule Drug Therapy Early Intervention Health Care Delivery Human Humans Maintenance Therapy Medical sciences Pharmacology. Drug treatments Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychosocial Rehabilitation Recurrence Schizophrenia Schizophrenia - drug therapy Schizophrenic Psychology
title	Early intervention, time-limited, targeted pharmacotherapy of schizophrenia
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