Hamster endogenous retrovirus (HaER) isolated from SV-40 induced tumor cells

A hamster cell line obtained from a secondary transplanted SV-40-induced tumor was found to spontaneously release type C virus particles. The particles possessed all biochemical features characteristic of retroviruses and induced syncytium formation in XC cells but were not oncogenic for hamsters. N...

Full description

Saved in:
Bibliographic Details
Published in:Archives of virology 1983, Vol.78 (3-4), p.233-244
Main Authors: GOLDSCHMIED-REOUVEN, A, YANIV, A, PERK, K
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cell Line
Centrifugation, Density Gradient
Cricetinae - microbiology
Cytopathogenic Effect, Viral
Fundamental and applied biological sciences. Psychology
Mesocricetus
Microbiology
Neoplasms, Experimental - etiology
Neoplasms, Experimental - microbiology
Retroviridae - isolation & purification
Retroviridae - ultrastructure
RNA, Viral - analysis
RNA-Directed DNA Polymerase - metabolism
Simian virus 40
Systematics
Tumor Virus Infections - microbiology
Virology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A hamster cell line obtained from a secondary transplanted SV-40-induced tumor was found to spontaneously release type C virus particles. The particles possessed all biochemical features characteristic of retroviruses and induced syncytium formation in XC cells but were not oncogenic for hamsters. Nucleic acid hybridization assays demonstrated that the isolated virus was an endogenous retrovirus of hamster, lacking sequence homology with mouse and other animal species.
ISSN:0304-8608
1432-8798
DOI:10.1007/BF01311318