New Microprocessor-Based Insulin Controller

We have previously defined the requirements of an elegant, simple waveform for intravenous insulin delivery in insulin-dependent diabetes [7]. This waveform consists of a constant basal rate and three sequential pulses which are adapted for each meal. Under the direction of a diabetologist, the basa...

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Bibliographic Details
Published in:IEEE transactions on biomedical engineering 1983-11, Vol.BME-30 (11), p.689-695
Main Authors: Marshall, Trevor G., Mekhiel, N., Jackman, W. S., Perlman, K., Albisser, A. M.
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Blood
Computers
Diabetes
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Humans
Insulin
Insulin Infusion Systems
Management. Various non-drug treatments. Langerhans islet grafts
Medical Laboratory Science
Medical sciences
Microcomputers
Microprocessors
Muscles
Pancreas
Proteins
Pulse amplifiers
Sugar
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Summary:We have previously defined the requirements of an elegant, simple waveform for intravenous insulin delivery in insulin-dependent diabetes [7]. This waveform consists of a constant basal rate and three sequential pulses which are adapted for each meal. Under the direction of a diabetologist, the basal rate is adjusted for fasting normal blood glucose levels, and the meal pulses are configured according to two parameters per pulse (flow rate and time duration) so that blood glucose after the meal is also normalized. We here describe a new microprocessor-based insulin controller which exploits this knowledge.
ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.1983.325181