A biphasic compartmentation of neuro-transmission associated metabolic patterns during electro-induced axoplasmic transport in sheep medulla oblongata

In the sheep medulla oblongata, on the induction of polarity by the applied voltage gradient of direct current along the length, the enzymes such as acetylcholinesterase and glutamate dehydrogenase showed anodal transport while the enzyme arginase showed cathodal transport indicating the possession...

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Bibliographic Details
Published in:Indian journal of physiology and pharmacology 1983-07, Vol.27 (3), p.221-226
Main Authors: Narasimham, P V, Mohanachari, V, Swami, K S, Indira, K
Format: Article
Language:English
Subjects:
Acetylcholinesterase - metabolism
Animals
Arginase - metabolism
Axonal Transport
Electric Stimulation
Electrophysiology
Glutamate Dehydrogenase - metabolism
In Vitro Techniques
Medulla Oblongata - physiology
Sheep - physiology
Synaptic Transmission
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Summary:In the sheep medulla oblongata, on the induction of polarity by the applied voltage gradient of direct current along the length, the enzymes such as acetylcholinesterase and glutamate dehydrogenase showed anodal transport while the enzyme arginase showed cathodal transport indicating the possession of negative and positive charge densities on the enzymes. These studies indicated that the glutamate bound metabolism, one towards ammonia formation and the other towards the energy production and neural transmission, have opposed electro-characteristics. The acetylcholinesterase system had anodal characteristics coupled to the glutamate dehydrogenase patterns. The existence of two charge based compartmentation is envisaged in the neural tissue.
ISSN:0019-5499