Immunochemical studies on Shigella dysenteriae type 10 bacterial polysaccharide

On graded hydrolysis and Smith degradation, the O-somatic polysaccharide isolated from Shigella dysenteriae type 10 bacteria yielded four oligosaccharides which were characterized by methylation studies. Immunochemical studies using constituent monosaccharides and the oligosaccharides indicated that...

Full description

Saved in:
Bibliographic Details
Published in:Carbohydrate research 1983-10, Vol.122 (2), p.257-267
Main Authors: Pal, Jitendra Nath, Rao, Chintala V.N., Chakraborty, Atindra N., Dastidar, Sujata Ghosh
Format: Article
Language:English
Subjects:
Bacteriology
Biogenesis of cell structures, supramolecular organization
Biological and medical sciences
Carbohydrate Conformation
Carbohydrate Sequence
Epitopes - analysis
Fundamental and applied biological sciences. Psychology
Microbiology
Oligosaccharides - analysis
Polysaccharides, Bacterial - immunology
Precipitin Tests
Shigella dysenteriae - immunology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:On graded hydrolysis and Smith degradation, the O-somatic polysaccharide isolated from Shigella dysenteriae type 10 bacteria yielded four oligosaccharides which were characterized by methylation studies. Immunochemical studies using constituent monosaccharides and the oligosaccharides indicated that the sugar grouping →3)-ManNAc-(1→3)-Rha-(1→4)-GlcNAc-(1→ was the immunodominant part in the polysaccharide molecule, and that 2-acetamido-2-deoxy- d-mannose contributed maximally to the immunological specificity of the macromolecule.
ISSN:0008-6215
1873-426X
DOI:10.1016/0008-6215(83)88337-2