Failure to demonstrate a chromosome 2 deletion in adenomatous colorectal polyposis patients

A group of researchers recently reported a specific chromosome abnormality consisting of a deletion in the long arm (q) of chromosome 2 in patients with adenomatous colorectal polyposis. Using a high resolution chromosome banding technique and a blind study design, the authors karyotyped two patient...

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Bibliographic Details
Published in:Cancer 1984-01, Vol.53 (2), p.317-318
Main Authors: Fineman, Robert M., Morgan, Martha, Burt, Randall W., Gardner, Eldon J.
Format: Article
Language:English
Subjects:
Adult
Chromosome Banding
Chromosome Deletion
Chromosomes, Human, 1-3
Colonic Neoplasms - genetics
Female
Humans
Male
Middle Aged
Polyps - genetics
Rectal Neoplasms - genetics
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Summary:A group of researchers recently reported a specific chromosome abnormality consisting of a deletion in the long arm (q) of chromosome 2 in patients with adenomatous colorectal polyposis. Using a high resolution chromosome banding technique and a blind study design, the authors karyotyped two patients with Gardner syndrome, two patients with familial polyposis, and four normal controls. No deletion was found in chromosome 2.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19840115)53:2<317::AID-CNCR2820530223>3.0.CO;2-C