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Failure to demonstrate a chromosome 2 deletion in adenomatous colorectal polyposis patients

A group of researchers recently reported a specific chromosome abnormality consisting of a deletion in the long arm (q) of chromosome 2 in patients with adenomatous colorectal polyposis. Using a high resolution chromosome banding technique and a blind study design, the authors karyotyped two patient...

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Published in:Cancer 1984-01, Vol.53 (2), p.317-318
Main Authors: Fineman, Robert M., Morgan, Martha, Burt, Randall W., Gardner, Eldon J.
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Language:English
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creator Fineman, Robert M.
Morgan, Martha
Burt, Randall W.
Gardner, Eldon J.
description A group of researchers recently reported a specific chromosome abnormality consisting of a deletion in the long arm (q) of chromosome 2 in patients with adenomatous colorectal polyposis. Using a high resolution chromosome banding technique and a blind study design, the authors karyotyped two patients with Gardner syndrome, two patients with familial polyposis, and four normal controls. No deletion was found in chromosome 2.
doi_str_mv 10.1002/1097-0142(19840115)53:2<317::AID-CNCR2820530223>3.0.CO;2-C
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subjects Adult
Chromosome Banding
Chromosome Deletion
Chromosomes, Human, 1-3
Colonic Neoplasms - genetics
Female
Humans
Male
Middle Aged
Polyps - genetics
Rectal Neoplasms - genetics
title Failure to demonstrate a chromosome 2 deletion in adenomatous colorectal polyposis patients
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