Distribution of Marihuana in Monkey Brain and Concomitant Behavioural Effects

MARIHUANA and hashish have been used for centuries and the literature abounds with references to their effects. Only recently, however, have carefully controlled studies attempted to relate dose level and route of administration of Δ 9 -tetrahydrocannabinol (Δ 9 -THC), the principal psychoactive con...

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Bibliographic Details
Published in:Nature (London) 1971-04, Vol.230 (5296), p.593-594
Main Authors: MCISAAC, WILLIAM M, FRITCHIE, G. EDWARD, IDÄNPÄÄN-HEIKKILÄ, J. E, HO, BENG T, ENGLERT, LEO. F
Format: Article
Language:English
Subjects:
Aggression - drug effects
Animals
Behavior, Animal - drug effects
Brain - metabolism
Brain Chemistry
Cannabis - administration & dosage
Cannabis - metabolism
Haplorhini
Humanities and Social Sciences
Humans
Injections, Intravenous
letter
Motor Activity - drug effects
multidisciplinary
Phytotherapy
Science
Science (multidisciplinary)
Tritium
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Summary:MARIHUANA and hashish have been used for centuries and the literature abounds with references to their effects. Only recently, however, have carefully controlled studies attempted to relate dose level and route of administration of Δ 9 -tetrahydrocannabinol (Δ 9 -THC), the principal psychoactive constituent of Cannabis sativa , to subjective and objective physiological, behavioural and mentational effects 1–3 . Attempts have also been made to compare the effects of Δ 9 -THC with those of ethanol 4 .
ISSN:0028-0836
1476-4687
DOI:10.1038/230593a0