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A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome
Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with thi...
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| Published in: | Science (American Association for the Advancement of Science) 1984-02, Vol.223 (4636), p.602-605 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c640t-1616811512ba38cb71fecda928e8bef25c5cf3e8187b3a7b1fff13539bcb380e3 |
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| cites | cdi_FETCH-LOGICAL-c640t-1616811512ba38cb71fecda928e8bef25c5cf3e8187b3a7b1fff13539bcb380e3 |
| container_end_page | 605 |
| container_issue | 4636 |
| container_start_page | 602 |
| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 223 |
| creator | Daniel, Muthiah D. King, Norval W. Letvin, Norman L. Hunt, Ronald D. Sehgal, Prabhat K. Desrosiers, Ronald C. |
| description | Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta). |
| doi_str_mv | 10.1126/science.6695172 |
| format | article |
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In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.6695172</identifier><identifier>PMID: 6695172</identifier><identifier>CODEN: SCIEAS</identifier><language>eng</language><publisher>Washington, DC: The American Association for the Advancement of Science</publisher><subject>AIDS (Disease) ; AIDS research ; AIDS/HIV ; Animals ; B lymphocytes ; Biological and medical sciences ; Burkitt Lymphoma ; Cell culture techniques ; Cell Line ; Cell lines ; Diseases ; DNA ; Hepatocytes ; Humans ; Immunodeficiencies. Immunoglobulinopathies ; Immunologic Deficiency Syndromes - microbiology ; Immunologic diseases ; Immunopathology ; Laboratory primates ; Lymphocytes ; Macaca ; Macaca cyclopis ; Macaques ; Medical sciences ; Nucleic Acid Hybridization ; Observations ; Physiological immunosuppression ; Primates as laboratory animals ; Retroviridae ; Retroviridae - genetics ; Retroviridae - immunology ; Retroviridae - isolation & purification ; T lymphocytes ; Viral research ; Virus research ; Viruses</subject><ispartof>Science (American Association for the Advancement of Science), 1984-02, Vol.223 (4636), p.602-605</ispartof><rights>Copyright 1984 The American Association for the Advancement of Science</rights><rights>1984 INIST-CNRS</rights><rights>COPYRIGHT 1984 American Association for the Advancement of Science</rights><rights>COPYRIGHT 1984 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c640t-1616811512ba38cb71fecda928e8bef25c5cf3e8187b3a7b1fff13539bcb380e3</citedby><cites>FETCH-LOGICAL-c640t-1616811512ba38cb71fecda928e8bef25c5cf3e8187b3a7b1fff13539bcb380e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2884,2885,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9679973$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6695172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Daniel, Muthiah D.</creatorcontrib><creatorcontrib>King, Norval W.</creatorcontrib><creatorcontrib>Letvin, Norman L.</creatorcontrib><creatorcontrib>Hunt, Ronald D.</creatorcontrib><creatorcontrib>Sehgal, Prabhat K.</creatorcontrib><creatorcontrib>Desrosiers, Ronald C.</creatorcontrib><title>A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).</description><subject>AIDS (Disease)</subject><subject>AIDS research</subject><subject>AIDS/HIV</subject><subject>Animals</subject><subject>B lymphocytes</subject><subject>Biological and medical sciences</subject><subject>Burkitt Lymphoma</subject><subject>Cell culture techniques</subject><subject>Cell Line</subject><subject>Cell lines</subject><subject>Diseases</subject><subject>DNA</subject><subject>Hepatocytes</subject><subject>Humans</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunologic Deficiency Syndromes - microbiology</subject><subject>Immunologic diseases</subject><subject>Immunopathology</subject><subject>Laboratory primates</subject><subject>Lymphocytes</subject><subject>Macaca</subject><subject>Macaca cyclopis</subject><subject>Macaques</subject><subject>Medical sciences</subject><subject>Nucleic Acid Hybridization</subject><subject>Observations</subject><subject>Physiological immunosuppression</subject><subject>Primates as laboratory animals</subject><subject>Retroviridae</subject><subject>Retroviridae - genetics</subject><subject>Retroviridae - immunology</subject><subject>Retroviridae - isolation & purification</subject><subject>T lymphocytes</subject><subject>Viral research</subject><subject>Virus research</subject><subject>Viruses</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><recordid>eNqN0s1v0zAUAHALgUY3OHMByQcEh9HNH4tjH0uBUqmsiA2uluM8l0xJXOxko_89Ho22IVWi8sGS38_2e3oPoReUnFDKxGm0FbQWToRQGc3ZIzSiRGVjxQh_jEaEcDGWJM-eosMYrwhJMcUP0MHAR-jrBJ_DDb7crAF_wN-gC_66Cn3E8-hr00GJXfAN_mKs-dVDxDdV9xObFs-bpm99Ca76m8AGX2zaMkl4hp44U0d4PuxH6Punj5fTz-PFcjafThZjK85IN6aCCklpRllhuLRFTh3Y0igmQRbgWGYz6zhIKvOCm7ygzjnKM64KW3BJgB-hN9t318HfZtbppooW6tq04PuoZSqVCXn2X0i5ZEpkNMHjLVyZGnTVOt8FY1fQQjC1b1Op6XjCKWdKsaTf7dBpldBUdgd_-w9PooPf3cr0Mer5xfm-cvljX_l-tqeUs8VDebxLWl_XsAKdWjhdPtSnW22DjzGA0-tQNSZsNCX6dj71MJ96GLh049XQjb5ooLzz9_HXQ9xEa2oXTGureMeUyJXKeWIvt-wqdj7c_yoUY1nG_wASM_QM</recordid><startdate>19840210</startdate><enddate>19840210</enddate><creator>Daniel, Muthiah D.</creator><creator>King, Norval W.</creator><creator>Letvin, Norman L.</creator><creator>Hunt, Ronald D.</creator><creator>Sehgal, Prabhat K.</creator><creator>Desrosiers, Ronald C.</creator><general>The American Association for the Advancement of Science</general><general>American Association for the Advancement of Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8GL</scope><scope>IBG</scope><scope>IOV</scope><scope>ISN</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19840210</creationdate><title>A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome</title><author>Daniel, Muthiah D. ; King, Norval W. ; Letvin, Norman L. ; Hunt, Ronald D. ; Sehgal, Prabhat K. ; Desrosiers, Ronald C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c640t-1616811512ba38cb71fecda928e8bef25c5cf3e8187b3a7b1fff13539bcb380e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>AIDS (Disease)</topic><topic>AIDS research</topic><topic>AIDS/HIV</topic><topic>Animals</topic><topic>B lymphocytes</topic><topic>Biological and medical sciences</topic><topic>Burkitt Lymphoma</topic><topic>Cell culture techniques</topic><topic>Cell Line</topic><topic>Cell lines</topic><topic>Diseases</topic><topic>DNA</topic><topic>Hepatocytes</topic><topic>Humans</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunologic Deficiency Syndromes - microbiology</topic><topic>Immunologic diseases</topic><topic>Immunopathology</topic><topic>Laboratory primates</topic><topic>Lymphocytes</topic><topic>Macaca</topic><topic>Macaca cyclopis</topic><topic>Macaques</topic><topic>Medical sciences</topic><topic>Nucleic Acid Hybridization</topic><topic>Observations</topic><topic>Physiological immunosuppression</topic><topic>Primates as laboratory animals</topic><topic>Retroviridae</topic><topic>Retroviridae - genetics</topic><topic>Retroviridae - immunology</topic><topic>Retroviridae - isolation & purification</topic><topic>T lymphocytes</topic><topic>Viral research</topic><topic>Virus research</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Daniel, Muthiah D.</creatorcontrib><creatorcontrib>King, Norval W.</creatorcontrib><creatorcontrib>Letvin, Norman L.</creatorcontrib><creatorcontrib>Hunt, Ronald D.</creatorcontrib><creatorcontrib>Sehgal, Prabhat K.</creatorcontrib><creatorcontrib>Desrosiers, Ronald C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: High School</collection><collection>Biography (Gale in Context)</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Canada</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Daniel, Muthiah D.</au><au>King, Norval W.</au><au>Letvin, Norman L.</au><au>Hunt, Ronald D.</au><au>Sehgal, Prabhat K.</au><au>Desrosiers, Ronald C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1984-02-10</date><risdate>1984</risdate><volume>223</volume><issue>4636</issue><spage>602</spage><epage>605</epage><pages>602-605</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><coden>SCIEAS</coden><abstract>Macaque monkeys with the recently described acquired immunodeficiency syndrome show a marked defect in T-lymphocyte function and die with opportunistic infections and lymphoproliferative abnormalities. In the study described here a new type D retrovirus was isolated from two Macaca cyclopis with this syndrome. This virus is related to, but distinct from, Mason-Pfizer monkey virus, a type D retrovirus previously isolated from a mammary tumor of a rhesus monkey (Macaca mulatta).</abstract><cop>Washington, DC</cop><pub>The American Association for the Advancement of Science</pub><pmid>6695172</pmid><doi>10.1126/science.6695172</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1984-02, Vol.223 (4636), p.602-605 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80952684 |
| source | American Association for the Advancement of Science |
| subjects | AIDS (Disease) AIDS research AIDS/HIV Animals B lymphocytes Biological and medical sciences Burkitt Lymphoma Cell culture techniques Cell Line Cell lines Diseases DNA Hepatocytes Humans Immunodeficiencies. Immunoglobulinopathies Immunologic Deficiency Syndromes - microbiology Immunologic diseases Immunopathology Laboratory primates Lymphocytes Macaca Macaca cyclopis Macaques Medical sciences Nucleic Acid Hybridization Observations Physiological immunosuppression Primates as laboratory animals Retroviridae Retroviridae - genetics Retroviridae - immunology Retroviridae - isolation & purification T lymphocytes Viral research Virus research Viruses |
| title | A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome |
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