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Does the DNA methylase Eco dam pair nucleotide sequences to form site-specific duplexes?
The Eco dam methylase is active on denatured DNA and single-stranded synthetic oligonucleotides containing GATC sites. The results suggest that on interaction with single-stranded oligonucleotides the Eco dam methylase is able to form a duplex structure within the GATC site, and that this duplex sit...
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Published in: | FEBS letters 1984-03, Vol.168 (1), p.166-168 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The
Eco dam methylase is active on denatured DNA and single-stranded synthetic oligonucleotides containing GATC sites. The results suggest that on interaction with single-stranded oligonucleotides the
Eco dam methylase is able to form a duplex structure within the GATC site, and that this duplex site is a substrate for enzyme. |
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ISSN: | 0014-5793 1873-3468 |
DOI: | 10.1016/0014-5793(84)80228-8 |