Non-Gonococcal Ophthalmitis Associated with Erythromycin Ointment Prophylaxis of Gonococcal Ophthalmia Neonatorum

Substitution of erythromycin ointment for silver nitrate in the prophylaxis of gonococcal ophthalmia neonatorum (GON) was accompanied by eight infections in 749 (1.1%) well-born and 21 infections in 285 (7.4%) intensive care infants during an eight-month period. This was significantly higher than pr...

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Bibliographic Details
Published in:Infection control : IC 1984-03, Vol.5 (3), p.138-140
Main Authors: Mooney, Barbara R., Green, Jon A., Epstein, Beverly J., Hashisaki, Peter A.
Format: Article
Language:English
Subjects:
Antibiotics
Bacteria
Bacterial Infections - epidemiology
Endophthalmitis - epidemiology
Erythromycin - therapeutic use
Humans
Iatrogenic Disease - epidemiology
Infant, Newborn
Infants
Infections
Intensive care
Liquids
Nitrates
Nursing
Ointments
Ophthalmia neonatorum
Ophthalmia Neonatorum - prevention & control
Ophthalmic Solutions
Silver
Silver Nitrate - therapeutic use
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Summary:Substitution of erythromycin ointment for silver nitrate in the prophylaxis of gonococcal ophthalmia neonatorum (GON) was accompanied by eight infections in 749 (1.1%) well-born and 21 infections in 285 (7.4%) intensive care infants during an eight-month period. This was significantly higher than previous rates of ophthalmitis during the use of silver nitrate, 0.3% (5/1877) and 2.1% (19/904) for well and intensive care infants, (P
ISSN:0195-9417
2327-9451
DOI:10.1017/s0195941700060008