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MATERNAL AND UMBILICAL CORD PLASMA NORADRENALINE CONCENTRATIONS DURING LABOUR WITH AND WITHOUT SEGMENTAL EXTRADURAL ANALGESIA, AND DURING CAESAREAN SECTION
Serial measurements of maternal and umbilical cord plasma noradernaline concentrations were obtained in 10 patients undergoing normal vaginal delivery with segmental extradural analgesia, in 10 patients undergoing normal vaginal delivery without extradural analgesia, and in 12 patients undergoing el...
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Published in: | British journal of anaesthesia : BJA 1984-03, Vol.56 (3), p.251-255 |
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container_title | British journal of anaesthesia : BJA |
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creator | JOUPPILA, R. PUOLAKKA, J. KAUPPILA, A. VUORI, J. |
description | Serial measurements of maternal and umbilical cord plasma noradernaline concentrations were obtained in 10 patients undergoing normal vaginal delivery with segmental extradural analgesia, in 10 patients undergoing normal vaginal delivery without extradural analgesia, and in 12 patients undergoing elective Caesarean section under general anaesthesia. Maternal noradrenaline concentrations increased significantly during delivery in all three groups, the peak concentrations occurring at delivery. However, the increase in the maternal noradrenaline concentration during delivery in the extradural group was lower than in the non-extradural group (P |
doi_str_mv | 10.1093/bja/56.3.251 |
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Maternal noradrenaline concentrations increased significantly during delivery in all three groups, the peak concentrations occurring at delivery. However, the increase in the maternal noradrenaline concentration during delivery in the extradural group was lower than in the non-extradural group (P<0.05). Umbilical venous and arterial concentrations of noradernaline were lower after Caesarean section than after vaginal delivery. However, extradural analgesia did not affect the fetal noradrenalinc concentrations. Since noradrenaline is probably required for the adaptation of the newborn to extrauterine life, the unaltered fetal response may be beneficial.</description><identifier>ISSN: 0007-0912</identifier><identifier>EISSN: 1471-6771</identifier><identifier>DOI: 10.1093/bja/56.3.251</identifier><identifier>PMID: 6704273</identifier><identifier>CODEN: BJANAD</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Abdominal surgery. Urology. Gynecology. Obstetrics ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia, Epidural ; Anesthesia, General ; Anesthesia, Obstetrical ; Anesthesia. Intensive care medicine. Transfusions. 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Maternal noradrenaline concentrations increased significantly during delivery in all three groups, the peak concentrations occurring at delivery. However, the increase in the maternal noradrenaline concentration during delivery in the extradural group was lower than in the non-extradural group (P<0.05). Umbilical venous and arterial concentrations of noradernaline were lower after Caesarean section than after vaginal delivery. However, extradural analgesia did not affect the fetal noradrenalinc concentrations. Since noradrenaline is probably required for the adaptation of the newborn to extrauterine life, the unaltered fetal response may be beneficial.</description><subject>Abdominal surgery. Urology. Gynecology. Obstetrics</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia, Epidural</subject><subject>Anesthesia, General</subject><subject>Anesthesia, Obstetrical</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cesarean Section</subject><subject>Female</subject><subject>Fetal Blood - analysis</subject><subject>Humans</subject><subject>Labor, Obstetric</subject><subject>Medical sciences</subject><subject>Norepinephrine - blood</subject><subject>Pregnancy</subject><subject>Stress, Physiological - physiopathology</subject><subject>Time Factors</subject><issn>0007-0912</issn><issn>1471-6771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><recordid>eNptkUuP0zAURi0EGsrAji1SFojVpGMncRwvPalpIqUJygNGbCzHcaQMfQxxi-C38Gdx2qgrVrb1nXt8dS8A7xFcIkj9-_ZJ3uNw6S89jF6ABQoIckNC0EuwgBASF1LkvQZvjHmCEBGP4htwExIYeMRfgL8bVvMyZ5nD8pXTbB7SLI3tKy7KlfMlY9WGOXlRslXJLZTm3CZ5zPO6ZHVa5JWzaso0XzsZeyia0vmW1snZNF2KpnYqvt5Y2hr5o62x9Pkrlq15lbK7MzsrYsYrVnKW26J4kr8Fr3q5NfrdfN6C5jOv48TNivXUpKsCPzq6RHat6jzdaoioh3ocqrDHkkYtQp1HlYRdi1rZ-xjiSMKw9TW1I4Gkb2Xn9cq_BZ8u3ufx8POkzVHsBqP0div3-nAyIkIQYltgwbsLqMaDMaPuxfM47OT4RyAopl0IuwuBQ-ELuwuLf5i9p3anuys8D9_mH-dcGiW3_Sj3ajBXjAYRJWeNe8EGc9S_r7Ecf1iTT7BIHr-LJPwaJBXEYuoyvPDazuzXoEdh1KD3SnfDqNVRdIfh__3-A36Np2M</recordid><startdate>198403</startdate><enddate>198403</enddate><creator>JOUPPILA, R.</creator><creator>PUOLAKKA, J.</creator><creator>KAUPPILA, A.</creator><creator>VUORI, J.</creator><general>Elsevier Ltd</general><general>Oxford University Press</general><scope>6I.</scope><scope>AAFTH</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198403</creationdate><title>MATERNAL AND UMBILICAL CORD PLASMA NORADRENALINE CONCENTRATIONS DURING LABOUR WITH AND WITHOUT SEGMENTAL EXTRADURAL ANALGESIA, AND DURING CAESAREAN SECTION</title><author>JOUPPILA, R. ; PUOLAKKA, J. ; KAUPPILA, A. ; VUORI, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-7adbcd2ebe01921f56c6f5a98b11d29ca0db1baf35058a06b3e991207fbad2fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Abdominal surgery. Urology. Gynecology. Obstetrics</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia, Epidural</topic><topic>Anesthesia, General</topic><topic>Anesthesia, Obstetrical</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cesarean Section</topic><topic>Female</topic><topic>Fetal Blood - analysis</topic><topic>Humans</topic><topic>Labor, Obstetric</topic><topic>Medical sciences</topic><topic>Norepinephrine - blood</topic><topic>Pregnancy</topic><topic>Stress, Physiological - physiopathology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JOUPPILA, R.</creatorcontrib><creatorcontrib>PUOLAKKA, J.</creatorcontrib><creatorcontrib>KAUPPILA, A.</creatorcontrib><creatorcontrib>VUORI, J.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of anaesthesia : BJA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JOUPPILA, R.</au><au>PUOLAKKA, J.</au><au>KAUPPILA, A.</au><au>VUORI, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MATERNAL AND UMBILICAL CORD PLASMA NORADRENALINE CONCENTRATIONS DURING LABOUR WITH AND WITHOUT SEGMENTAL EXTRADURAL ANALGESIA, AND DURING CAESAREAN SECTION</atitle><jtitle>British journal of anaesthesia : BJA</jtitle><addtitle>Br J Anaesth</addtitle><date>1984-03</date><risdate>1984</risdate><volume>56</volume><issue>3</issue><spage>251</spage><epage>255</epage><pages>251-255</pages><issn>0007-0912</issn><eissn>1471-6771</eissn><coden>BJANAD</coden><abstract>Serial measurements of maternal and umbilical cord plasma noradernaline concentrations were obtained in 10 patients undergoing normal vaginal delivery with segmental extradural analgesia, in 10 patients undergoing normal vaginal delivery without extradural analgesia, and in 12 patients undergoing elective Caesarean section under general anaesthesia. Maternal noradrenaline concentrations increased significantly during delivery in all three groups, the peak concentrations occurring at delivery. However, the increase in the maternal noradrenaline concentration during delivery in the extradural group was lower than in the non-extradural group (P<0.05). Umbilical venous and arterial concentrations of noradernaline were lower after Caesarean section than after vaginal delivery. However, extradural analgesia did not affect the fetal noradrenalinc concentrations. Since noradrenaline is probably required for the adaptation of the newborn to extrauterine life, the unaltered fetal response may be beneficial.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>6704273</pmid><doi>10.1093/bja/56.3.251</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abdominal surgery. Urology. Gynecology. Obstetrics Anesthesia Anesthesia depending on type of surgery Anesthesia, Epidural Anesthesia, General Anesthesia, Obstetrical Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cesarean Section Female Fetal Blood - analysis Humans Labor, Obstetric Medical sciences Norepinephrine - blood Pregnancy Stress, Physiological - physiopathology Time Factors |
title | MATERNAL AND UMBILICAL CORD PLASMA NORADRENALINE CONCENTRATIONS DURING LABOUR WITH AND WITHOUT SEGMENTAL EXTRADURAL ANALGESIA, AND DURING CAESAREAN SECTION |
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