Identification of HLA-B44 subtypes associated with extended MHC haplotypes

The HLA class I antigen B44 is found in each of two different extended major histocompatibility haplotypes (allele combinations of HLA-B, HLA-DR, and complement genes BF, C2, C4A, and C4B in linkage disequilibrium). Using isoelectric focusing, two variants of HLA-B44 were identified. The basic varia...

Full description

Saved in:
Bibliographic Details
Published in:Immunogenetics (New York) 1987-01, Vol.26 (4-5), p.216-219
Main Authors: KRUSKALL, M. S, EYNON, E. E, AWDEH, Z, ALPER, C. A, YUNIS, E. J
Format: Article
Language:English
Subjects:
Applied sciences
Cell Line
Exact sciences and technology
Genetic Variation
Haplotypes
HLA Antigens - classification
HLA Antigens - genetics
HLA-B Antigens
HLA-B44 Antigen
Humans
Isoelectric Focusing
Major Histocompatibility Complex
Other techniques and industries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453
cites cdi_FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453
container_end_page 219
container_issue 4-5
container_start_page 216
container_title Immunogenetics (New York)
container_volume 26
creator KRUSKALL, M. S
EYNON, E. E
AWDEH, Z
ALPER, C. A
YUNIS, E. J
description The HLA class I antigen B44 is found in each of two different extended major histocompatibility haplotypes (allele combinations of HLA-B, HLA-DR, and complement genes BF, C2, C4A, and C4B in linkage disequilibrium). Using isoelectric focusing, two variants of HLA-B44 were identified. The basic variant was found in all cell lines with the extended haplotype HLA-B44, DR7, FC31, and the acidic variant in all cell lines with the extended haplotype HLA-B44, DR4, SC30. The occurrence of each antigen variant with a unique extended haplotype explains previous observations concerning the nonrandom association of B44 variants with DR antigens.
doi_str_mv 10.1007/BF00346515
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81011433</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>14826933</sourcerecordid><originalsourceid>FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453</originalsourceid><addsrcrecordid>eNqF0L1Lw1AUBfCHKLVWF3chgzgI0XffZzK2xVql4qJzeJ80kiYxL0H73xvbUEeny-X8OMNB6BLwHWAs72cLjCkTHPgRGgOjJAYCcIzGGKc0lhLgFJ2F8IEx8JSIERpRwWlK0zF6frKubHOfG9XmVRlVPlqupvGMsSh0ut3WLkQqhMrkqnU2-srbdeS-W1fa_ntZzqO1qotq587RiVdFcBfDnaD3xcPbfBmvXh-f5tNVbGhC29gIRbUEqjlLEou15FRJwQ331ieeaWsd90pxxo3SOhUKJIEUAyGaYsI4naCbfW_dVJ-dC222yYNxRaFKV3UhSwBDPwL9FwJLiEh38HYPTVOF0Dif1U2-Uc02A5z9Lpz9Ldzjq6G10xtnD3SYtM-vh1wFowrfqNLk4cBkwkSCOf0BY3aAtw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14826933</pqid></control><display><type>article</type><title>Identification of HLA-B44 subtypes associated with extended MHC haplotypes</title><source>SpringerLink_过刊（NSTL购买）</source><creator>KRUSKALL, M. S ; EYNON, E. E ; AWDEH, Z ; ALPER, C. A ; YUNIS, E. J</creator><creatorcontrib>KRUSKALL, M. S ; EYNON, E. E ; AWDEH, Z ; ALPER, C. A ; YUNIS, E. J</creatorcontrib><description>The HLA class I antigen B44 is found in each of two different extended major histocompatibility haplotypes (allele combinations of HLA-B, HLA-DR, and complement genes BF, C2, C4A, and C4B in linkage disequilibrium). Using isoelectric focusing, two variants of HLA-B44 were identified. The basic variant was found in all cell lines with the extended haplotype HLA-B44, DR7, FC31, and the acidic variant in all cell lines with the extended haplotype HLA-B44, DR4, SC30. The occurrence of each antigen variant with a unique extended haplotype explains previous observations concerning the nonrandom association of B44 variants with DR antigens.</description><identifier>ISSN: 0093-7711</identifier><identifier>EISSN: 1432-1211</identifier><identifier>DOI: 10.1007/BF00346515</identifier><identifier>PMID: 3653939</identifier><identifier>CODEN: IMNGBK</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Applied sciences ; Cell Line ; Exact sciences and technology ; Genetic Variation ; Haplotypes ; HLA Antigens - classification ; HLA Antigens - genetics ; HLA-B Antigens ; HLA-B44 Antigen ; Humans ; Isoelectric Focusing ; Major Histocompatibility Complex ; Other techniques and industries</subject><ispartof>Immunogenetics (New York), 1987-01, Vol.26 (4-5), p.216-219</ispartof><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453</citedby><cites>FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=7846805$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3653939$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KRUSKALL, M. S</creatorcontrib><creatorcontrib>EYNON, E. E</creatorcontrib><creatorcontrib>AWDEH, Z</creatorcontrib><creatorcontrib>ALPER, C. A</creatorcontrib><creatorcontrib>YUNIS, E. J</creatorcontrib><title>Identification of HLA-B44 subtypes associated with extended MHC haplotypes</title><title>Immunogenetics (New York)</title><addtitle>Immunogenetics</addtitle><description>The HLA class I antigen B44 is found in each of two different extended major histocompatibility haplotypes (allele combinations of HLA-B, HLA-DR, and complement genes BF, C2, C4A, and C4B in linkage disequilibrium). Using isoelectric focusing, two variants of HLA-B44 were identified. The basic variant was found in all cell lines with the extended haplotype HLA-B44, DR7, FC31, and the acidic variant in all cell lines with the extended haplotype HLA-B44, DR4, SC30. The occurrence of each antigen variant with a unique extended haplotype explains previous observations concerning the nonrandom association of B44 variants with DR antigens.</description><subject>Applied sciences</subject><subject>Cell Line</subject><subject>Exact sciences and technology</subject><subject>Genetic Variation</subject><subject>Haplotypes</subject><subject>HLA Antigens - classification</subject><subject>HLA Antigens - genetics</subject><subject>HLA-B Antigens</subject><subject>HLA-B44 Antigen</subject><subject>Humans</subject><subject>Isoelectric Focusing</subject><subject>Major Histocompatibility Complex</subject><subject>Other techniques and industries</subject><issn>0093-7711</issn><issn>1432-1211</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><recordid>eNqF0L1Lw1AUBfCHKLVWF3chgzgI0XffZzK2xVql4qJzeJ80kiYxL0H73xvbUEeny-X8OMNB6BLwHWAs72cLjCkTHPgRGgOjJAYCcIzGGKc0lhLgFJ2F8IEx8JSIERpRwWlK0zF6frKubHOfG9XmVRlVPlqupvGMsSh0ut3WLkQqhMrkqnU2-srbdeS-W1fa_ntZzqO1qotq587RiVdFcBfDnaD3xcPbfBmvXh-f5tNVbGhC29gIRbUEqjlLEou15FRJwQ331ieeaWsd90pxxo3SOhUKJIEUAyGaYsI4naCbfW_dVJ-dC222yYNxRaFKV3UhSwBDPwL9FwJLiEh38HYPTVOF0Dif1U2-Uc02A5z9Lpz9Ldzjq6G10xtnD3SYtM-vh1wFowrfqNLk4cBkwkSCOf0BY3aAtw</recordid><startdate>19870101</startdate><enddate>19870101</enddate><creator>KRUSKALL, M. S</creator><creator>EYNON, E. E</creator><creator>AWDEH, Z</creator><creator>ALPER, C. A</creator><creator>YUNIS, E. J</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19870101</creationdate><title>Identification of HLA-B44 subtypes associated with extended MHC haplotypes</title><author>KRUSKALL, M. S ; EYNON, E. E ; AWDEH, Z ; ALPER, C. A ; YUNIS, E. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Applied sciences</topic><topic>Cell Line</topic><topic>Exact sciences and technology</topic><topic>Genetic Variation</topic><topic>Haplotypes</topic><topic>HLA Antigens - classification</topic><topic>HLA Antigens - genetics</topic><topic>HLA-B Antigens</topic><topic>HLA-B44 Antigen</topic><topic>Humans</topic><topic>Isoelectric Focusing</topic><topic>Major Histocompatibility Complex</topic><topic>Other techniques and industries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KRUSKALL, M. S</creatorcontrib><creatorcontrib>EYNON, E. E</creatorcontrib><creatorcontrib>AWDEH, Z</creatorcontrib><creatorcontrib>ALPER, C. A</creatorcontrib><creatorcontrib>YUNIS, E. J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Immunogenetics (New York)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KRUSKALL, M. S</au><au>EYNON, E. E</au><au>AWDEH, Z</au><au>ALPER, C. A</au><au>YUNIS, E. J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of HLA-B44 subtypes associated with extended MHC haplotypes</atitle><jtitle>Immunogenetics (New York)</jtitle><addtitle>Immunogenetics</addtitle><date>1987-01-01</date><risdate>1987</risdate><volume>26</volume><issue>4-5</issue><spage>216</spage><epage>219</epage><pages>216-219</pages><issn>0093-7711</issn><eissn>1432-1211</eissn><coden>IMNGBK</coden><abstract>The HLA class I antigen B44 is found in each of two different extended major histocompatibility haplotypes (allele combinations of HLA-B, HLA-DR, and complement genes BF, C2, C4A, and C4B in linkage disequilibrium). Using isoelectric focusing, two variants of HLA-B44 were identified. The basic variant was found in all cell lines with the extended haplotype HLA-B44, DR7, FC31, and the acidic variant in all cell lines with the extended haplotype HLA-B44, DR4, SC30. The occurrence of each antigen variant with a unique extended haplotype explains previous observations concerning the nonrandom association of B44 variants with DR antigens.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>3653939</pmid><doi>10.1007/BF00346515</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0093-7711
ispartof Immunogenetics (New York), 1987-01, Vol.26 (4-5), p.216-219
issn 0093-7711
1432-1211
language eng
recordid cdi_proquest_miscellaneous_81011433
source SpringerLink_过刊（NSTL购买）
subjects Applied sciences
Cell Line
Exact sciences and technology
Genetic Variation
Haplotypes
HLA Antigens - classification
HLA Antigens - genetics
HLA-B Antigens
HLA-B44 Antigen
Humans
Isoelectric Focusing
Major Histocompatibility Complex
Other techniques and industries
title Identification of HLA-B44 subtypes associated with extended MHC haplotypes
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T16%3A02%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Identification%20of%20HLA-B44%20subtypes%20associated%20with%20extended%20MHC%20haplotypes&rft.jtitle=Immunogenetics%20(New%20York)&rft.au=KRUSKALL,%20M.%20S&rft.date=1987-01-01&rft.volume=26&rft.issue=4-5&rft.spage=216&rft.epage=219&rft.pages=216-219&rft.issn=0093-7711&rft.eissn=1432-1211&rft.coden=IMNGBK&rft_id=info:doi/10.1007/BF00346515&rft_dat=%3Cproquest_cross%3E14826933%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c383t-c6a3b713b5488d0b753a765c5fdf8f4bdde5faa545cabb96a172190122b302453%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=14826933&rft_id=info:pmid/3653939&rfr_iscdi=true