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Radionuclide evaluation of aortic regurgitation: assessment of ventricular function by Fourier phase analysis

Forty patients with chronic isolated aortic regurgitation were studied by phase analysis of equilibrium radionuclide ventriculography to see whether this technique could detect changes in left ventricular (LV) function before the onset of symptoms. This technique was compared to the radionuclide eje...

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Published in:European heart journal 1987-07, Vol.8 (7), p.702-709
Main Authors: ORMEROD, O. J. M., BARBER, R. W., STONE, D. L., MURFET, H., WRAIGHT, E. P., PETCH, M. C.
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container_end_page 709
container_issue 7
container_start_page 702
container_title European heart journal
container_volume 8
creator ORMEROD, O. J. M.
BARBER, R. W.
STONE, D. L.
MURFET, H.
WRAIGHT, E. P.
PETCH, M. C.
description Forty patients with chronic isolated aortic regurgitation were studied by phase analysis of equilibrium radionuclide ventriculography to see whether this technique could detect changes in left ventricular (LV) function before the onset of symptoms. This technique was compared to the radionuclide ejection fraction and echocardiography. The severity of LV volume overload was assessed using the radionuclide regurgitant index. Patients with clinically severe aortic regurgitation had severe volume overload (high regurgitant index), increased echocardiographic left ventricular dimensions and significantly increased phase spread (loss synchrony of wall motion) compared to mild and moderate groups. All but one had well maintained global left ventricular function assessed by the ejection fraction. All seven patients with definite symptoms had a marked increase in phase spread and severe volume overload.
doi_str_mv 10.1093/eurheartj/8.7.702
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source Oxford University Press:Jisc Collections:Oxford Journal Archive: Access period 2024-2025
subjects Adult
Aortic regurgitation
Aortic Valve Insufficiency - diagnostic imaging
Echocardiography
Female
Fourier Analysis
Fourier phase analysis
Heart - diagnostic imaging
Humans
Male
Myocardial Contraction
Radionuclide Imaging
radionuclide ventriculography
Stroke Volume
title Radionuclide evaluation of aortic regurgitation: assessment of ventricular function by Fourier phase analysis
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