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Pre- and post-operative changes in serum immunoglobulin level in neurosurgical patients

46 patients treated by operative neurosurgery for spontaneous subarachnoid haemorrhage, intracranial tumour and spinal diseases were studied. Levels of circulating immunoglobulin and complement were measured pre-operatively and serially in the first 10 post-operative days. Prior to operation immunog...

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Published in:	Acta neurochirurgica 1984-09, Vol.70 (3-4), p.269-274
Main Authors:	SEELDRAYERS, P. A, HOYLE, N. R, THOMAS, D. G. T
Format:	Article
Language:	English
Subjects:	Biological and medical sciences Complement C3 - analysis Female Humans Immunoglobulin A - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Male Medical sciences Middle Aged Nervous System Diseases - blood Nervous System Diseases - surgery Postoperative Period Preoperative Care Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the respiratory system
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description	46 patients treated by operative neurosurgery for spontaneous subarachnoid haemorrhage, intracranial tumour and spinal diseases were studied. Levels of circulating immunoglobulin and complement were measured pre-operatively and serially in the first 10 post-operative days. Prior to operation immunoglobulin levels in all categories of patients were distributed normally. However, immediately post-operatively IgG and IgM fell sharply. Conversely IgA rose in a marked manner and C3 levels showed a gradual increase. Later, antibody levels tended to return to normal.
doi_str_mv	10.1007/BF01406655
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Later, antibody levels tended to return to normal.</description><subject>Biological and medical sciences</subject><subject>Complement C3 - analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Immunoglobulin A - analysis</subject><subject>Immunoglobulin G - analysis</subject><subject>Immunoglobulin M - analysis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous System Diseases - blood</subject><subject>Nervous System Diseases - surgery</subject><subject>Postoperative Period</subject><subject>Preoperative Care</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Graft diseases</topic><topic>Surgery of the respiratory system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SEELDRAYERS, P. A</creatorcontrib><creatorcontrib>HOYLE, N. R</creatorcontrib><creatorcontrib>THOMAS, D. G. T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta neurochirurgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SEELDRAYERS, P. A</au><au>HOYLE, N. R</au><au>THOMAS, D. G. 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subjects	Biological and medical sciences Complement C3 - analysis Female Humans Immunoglobulin A - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Male Medical sciences Middle Aged Nervous System Diseases - blood Nervous System Diseases - surgery Postoperative Period Preoperative Care Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the respiratory system
title	Pre- and post-operative changes in serum immunoglobulin level in neurosurgical patients
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