Non-A, Non-B Hepatitis: Etiology and Clinical Course

It is currently believed that non-A, non-B hepatitis represents several different viral infections. Although the condition is clearly distinct from common cases of hepatitis A and B, new forms of non-A, non-B hepatitis have recently been found that share some characteristics with these diseases. Rel...

Full description

Saved in:
Bibliographic Details
Published in:Annual review of medicine 1984-01, Vol.35 (1), p.265-278
Main Author: Gitnick, G
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal
Antigen-Antibody Complex - immunology
Autoantibodies - immunology
Biological and medical sciences
Diagnosis, Differential
Hepatitis B Surface Antigens - immunology
Hepatitis C - diagnosis
Hepatitis C - etiology
Hepatitis C - immunology
Hepatitis C - transmission
Hepatitis Viruses - immunology
Hepatitis, Chronic - diagnosis
Hepatitis, Chronic - etiology
Hepatitis, Viral, Human - etiology
Human viral diseases
Humans
Infectious diseases
Medical sciences
Prognosis
Serologic Tests
Viral diseases
Viral hepatitis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is currently believed that non-A, non-B hepatitis represents several different viral infections. Although the condition is clearly distinct from common cases of hepatitis A and B, new forms of non-A, non-B hepatitis have recently been found that share some characteristics with these diseases. Reliable serologic assays do not exist, but animal transmission and electron microscopic studies indicate the presence of more than one viral agent. The great risk of chronicity following post-transfusion non-A, non-B hepatitis contrasts with the infrequent chronicity of sporadic non-A, non-B disease. Chronic non-A, non-B hepatitis is usually clinically inapparent with mild biochemical abnormalities; nevertheless, it slowly but relentlessly progresses to cirrhosis and portal hypertension.
ISSN:0066-4219
1545-326X
DOI:10.1146/annurev.me.35.020184.001405