Aetiology of recurrent aphthous ulcers (RAU)

A significant decrease in the pH of saliva has been detected in patients with recurrent aphthous ulcers (RAU). The decreae in pH was more prominent at night than between meals, and some persistent decrease was noticed even after recovery. The total proteins of saliva in RAU were also significantly d...

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Bibliographic Details
Published in:Journal of laryngology and otology 1987-09, Vol.101 (9), p.917-920
Main Authors: Maurice, Monir, Mikhail, Wadie, Aziz, Medhat, Barsoum, Maged
Format: Article
Language:English
Subjects:
Humans
Hydrogen-Ion Concentration
Recurrence
Saliva - metabolism
Stomatitis, Aphthous - etiology
Stomatitis, Aphthous - metabolism
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Summary:A significant decrease in the pH of saliva has been detected in patients with recurrent aphthous ulcers (RAU). The decreae in pH was more prominent at night than between meals, and some persistent decrease was noticed even after recovery. The total proteins of saliva in RAU were also significantly decreased. These findings were similar to those observed in patients complaining of petic ulcers, so it is recommended that patients with RAU should be treated with antacids as well as anticholinergic drugs, and that the possibility of concomitant peptic ulceration should also be investigated.
ISSN:0022-2151
1748-5460
DOI:10.1017/S002221510010297X