Neonatal Lupus with Congenital Atrioventricular Block and Myocarditis

This is a case of a child with neonatal lupus and congenital atrioventricuiar (AV) block, born to a mother with asymptomatic, systemic lupus erythematosus (SLE). The child, despite pacemaker insertion, died of septicemia and myocarditis at the age of three months. Although the association of neonata...

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Bibliographic Details
Published in:Pacing and clinical electrophysiology 1987-09, Vol.10 (5), p.1058-1070
Main Authors: BHARATI, SAROJA, SWERDLOW, MARTIN A., VITULLO, DOLORES, CHIEMMONGKOLTIP, PIPIT, LEV, MAURICE
Format: Article
Language:English
Subjects:
congenital AV block
Female
Heart Block - congenital
Heart Block - etiology
Heart Block - pathology
Humans
Infant, Newborn
lupus erythematosus
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - congenital
myocarditis
Myocarditis - etiology
Myocardium - pathology
Sepsis - etiology
septicemia
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Summary:This is a case of a child with neonatal lupus and congenital atrioventricuiar (AV) block, born to a mother with asymptomatic, systemic lupus erythematosus (SLE). The child, despite pacemaker insertion, died of septicemia and myocarditis at the age of three months. Although the association of neonatal lupus with congenital AV block is well‐recognized, there are only few pathologic studies of the conduction system reported in the literature. This is such a study in which we emphasize that, due to an altered immune system in the child, septicemia may be the cause of death in some cases.
ISSN:0147-8389
1540-8159
DOI:10.1111/j.1540-8159.1987.tb06125.x