Response of an Abnormal Sinus Node to Intravenous Flecainide Acetate

A patient with sinus node disease underwent provocative testing with flecainide, a new Vaughan Williams class IC antiarrhythmic agent. There were dramatic increases in sinus node recovery times and in Sinoatrial conduction times, and the magnitude of the response could only be witnessed because of t...

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Bibliographic Details
Published in:Pacing and clinical electrophysiology 1984-05, Vol.7 (3), p.436-439
Main Authors: HELLESTRAND, KEVIN J., NATHAN, ANTHONY W., BEXTON, RODNEY S., CAMM, A. JOHN
Format: Article
Language:English
Subjects:
Aged
Arrhythmia, Sinus - physiopathology
Electrocardiography
Female
Flecainide
Humans
junctional rhythm
Piperidines - pharmacology
sinoatrial conduction time
Sinoatrial Node - drug effects
Sinoatrial Node - physiopathology
sinus node disease
sinus node recovery time
Time Factors
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Summary:A patient with sinus node disease underwent provocative testing with flecainide, a new Vaughan Williams class IC antiarrhythmic agent. There were dramatic increases in sinus node recovery times and in Sinoatrial conduction times, and the magnitude of the response could only be witnessed because of the emergence of a subsidiary junctional pacemaker without retrograde conduction to the atria.
ISSN:0147-8389
1540-8159
DOI:10.1111/j.1540-8159.1984.tb04928.x