Nonconversion of o,p′-DDT to p,p′-DDT in Rats, Sheep, Chickens, and Quail

The finding of appreciable quantities of p,p′-DDT after feeding o,p′-DDT to rats led to the proposal of a theory that an isomeric metabolic conversion occurs. The presence of p,p′-DDT as an impurity in supposedly pure samples of o,p′-DDT is the correct explanation for the appearance of p,p′-DDT. Pur...

Full description

Saved in:
Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1971-10, Vol.174 (4004), p.64-66
Main Authors: Bitman, Joel, Cecil, Helene C., Fries, George F.
Format: Article
Language:English
Subjects:
Adipose Tissue - analysis
Animals
Autoradiography
Biotransformation
Birds
Body fat
Carbon Isotopes
Chickens
Chromatography, Thin Layer
DDT - administration & dosage
DDT - analysis
DDT - metabolism
Diet
Female
Impurities
Isomers
Japanese quails
Lipids
Pesticides
Radioactive decay
Rats
Sheep
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The finding of appreciable quantities of p,p′-DDT after feeding o,p′-DDT to rats led to the proposal of a theory that an isomeric metabolic conversion occurs. The presence of p,p′-DDT as an impurity in supposedly pure samples of o,p′-DDT is the correct explanation for the appearance of p,p′-DDT. Purified o,p′-DDT and $^{14}$C-labeled o,p′-DDT yielded no data to support the idea that o,p′-DDT is converted to the p,p′-DDT isomer.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.174.4004.64