Elevated ANA titers in patients with severely abnormal gastrointestinal motility

We studied a group of six patients with clinical, radiological, and/or manometric features of severely abnormal gastrointestinal motility. Symptoms suggestive of esophageal, small bowel, or colonic involvement were present from 1 1/2 to 40 years. All patients had elevated antinuclear antibody (ANA)...

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Bibliographic Details
Published in:Digestive diseases and sciences 1984-08, Vol.29 (8), p.735-739
Main Authors: SOFFER, E. E, STROTTMANN, M. P, ANURAS, S
Format: Article
Language:English
Subjects:
Aged
Antibodies, Antinuclear - analysis
Biological and medical sciences
Constipation - immunology
Constipation - physiopathology
Esophagus - diagnostic imaging
Female
Gastroenterology. Liver. Pancreas. Abdomen
Gastrointestinal Motility
Humans
Intestinal Pseudo-Obstruction - immunology
Intestinal Pseudo-Obstruction - physiopathology
Intestines - diagnostic imaging
Jejunum - physiopathology
Male
Manometry
Medical sciences
Middle Aged
Other diseases. Semiology
Radiography
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Summary:We studied a group of six patients with clinical, radiological, and/or manometric features of severely abnormal gastrointestinal motility. Symptoms suggestive of esophageal, small bowel, or colonic involvement were present from 1 1/2 to 40 years. All patients had elevated antinuclear antibody (ANA) titers. None had clinical or radiographic features suggestive of progressive systemic sclerosis or other connective tissue diseases. Two patients had pathologic examinations of intestinal specimens, and these did not show changes suggestive of progressive systemic sclerosis. We conclude that patients with severe gastrointestinal motility disorders can have elevated ANA titers without features of progressive systemic sclerosis or other connective tissue diseases.
ISSN:0163-2116
1573-2568
DOI:10.1007/BF01312947