Detection of Hepatitis B Viral DNA in Sera Positive for Antibody to Delta Antigen

Hepatitis B virus (HBV) DNA was detected in 17 sera positive for antibody to δ antigen (anti-δ). Six sera from two patients were positive for HBV DNA. Analysis by the Southern blot technique showed identity between HBV DNA in anti-δ-positive and anti-δ-negative sera. These results show that anti-δ-p...

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Bibliographic Details
Published in:The Journal of infectious diseases 1984-07, Vol.150 (1), p.118-120
Main Authors: Theilmann, L., Gmelin, K., Will, H., Czygan, P., Roggendorf, M., Kommerell, B.
Format: Article
Language:English
Subjects:
Antibodies
Antigens
Biological and medical sciences
Cellulose nitrate
DNA
DNA, Viral - blood
Hepatitis antigens
Hepatitis B
Hepatitis B - blood
Hepatitis B - immunology
Hepatitis B - microbiology
Hepatitis B Antibodies - analysis
Hepatitis B Antigens - immunology
Hepatitis B e Antigens - immunology
Hepatitis B Surface Antigens - analysis
Hepatitis B virus
Hepatitis B virus - genetics
Hepatitis delta Antigens
Human viral diseases
Humans
Infections
Infectious diseases
Liver
Medical sciences
Nucleic Acid Hybridization
Original Articles
Viral diseases
Viral DNA
Viral hepatitis
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Summary:Hepatitis B virus (HBV) DNA was detected in 17 sera positive for antibody to δ antigen (anti-δ). Six sera from two patients were positive for HBV DNA. Analysis by the Southern blot technique showed identity between HBV DNA in anti-δ-positive and anti-δ-negative sera. These results show that anti-δ-positive sera contain HBV DNA, although these sera were also positive for antibodies to hepatitis B e antigen.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/150.1.118