Effects of kidney transplantation on cognitive performance in a pediatric population

The cognitive functioning of 20 children and adolescents with end-stage renal disease was assessed 1 to 3 weeks prior to the onset of hemodialysis, and at 1 month and 1 year after successful kidney transplantation, and results were compared with those of a matched control group. A battery of intelli...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 1984-08, Vol.74 (2), p.273-278
Main Authors: FENNELL, R. S. III, RASBURY, W. C, FENNELL, E. B, MORRIS, M. K
Format: Article
Language:English
Subjects:
Achievement
Adolescent
Biological and medical sciences
Child
Humans
Intelligence
Kidney Failure, Chronic - psychology
Kidney Failure, Chronic - surgery
Kidney Failure, Chronic - therapy
Kidney Transplantation
Medical sciences
Prospective Studies
Psychological Tests
Renal Dialysis
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Time Factors
Wechsler Scales
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The cognitive functioning of 20 children and adolescents with end-stage renal disease was assessed 1 to 3 weeks prior to the onset of hemodialysis, and at 1 month and 1 year after successful kidney transplantation, and results were compared with those of a matched control group. A battery of intelligence, achievement, problem solving, learning, memory, and attention tasks were administered. Both groups had significantly improved scores over time on most measures. The group with renal disease exhibited significantly greater improvement than the control group from initial testing to 1 month after transplantation on the performance IQ and full-scale IQ as well as in mathematics achievement. This significant difference was not maintained, however, at 1 year after transplantation. Cognitive performance was less impaired the later the onset of renal failure or the fewer the years in end-stage renal disease. BUN nitrogen, serum creatinine levels, and BP did not consistently correlate with any of the cognitive or academic achievement measures.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.74.2.273