Oligomycin sensitivity-conferring protein (OSCP) of beef heart mitochondria: Internal sequence homology and structural relationship with other proteins

Structural analysis of oligomycin sensitivity-conferring protein (OSCP) revealed repeating sequences (residues 1-89, 105-190) suggesting an evolution of the protein by gene duplication. In addition to the reported homology with the δ-subunit of Escherichia coli F 1ATPase, OSCP also shows a certain h...

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Bibliographic Details
Published in:FEBS letters 1984-09, Vol.175 (1), p.109-112
Main Authors: Ovchinnikov, Yu.A., Modyanov, N.N., Grinkevich, V.A., Aldanova, N.A., Kostetsky, P.V., Trubetskaya, O.E., Hundal, T., Ernster, L.
Format: Article
Language:English
Subjects:
Adenosine Triphosphatases - isolation & purification
Amino Acid Sequence
Animals
Carrier Proteins - isolation & purification
Cattle
Comparative analysis
coupling factor 0
coupling factor 1
Escherichia coli
F 0F 1
heart
homology
Macromolecular Substances
Membrane Proteins - isolation & purification
Mitochondria, Heart - metabolism
Mitochondrial ADP, ATP Translocases
Oligomycin sensitivity-conferring protein
Sequence
Software
Structural relationship
Structure-Activity Relationship
Subunit
Citations: Items that this one cites
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Summary:Structural analysis of oligomycin sensitivity-conferring protein (OSCP) revealed repeating sequences (residues 1-89, 105-190) suggesting an evolution of the protein by gene duplication. In addition to the reported homology with the δ-subunit of Escherichia coli F 1ATPase, OSCP also shows a certain homology with the b-subunit of E. coli F 0 and the ADP/ATP carrier of mitochondria.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(84)80580-3