Pit Cell‐Hepatocyte Contact in Autoimmune Hepatitis

This is the first report to document pit cells in the human liver. These cells were identified by characteristic electron‐dense granules and rod‐cored vesicles. The granules of human pit cells were smaller in number and size than those of the rat. In the present case of autoimmune hepatitis, pit cel...

Full description

Saved in:
Bibliographic Details
Published in:Hepatology (Baltimore, Md.) Md.), 1984-09, Vol.4 (5), p.955-958
Main Authors: Kaneda, Kenji, Kurioka, Narito, Seki, Shuichi, Wake, Kenjiro, Yamamoto, Sukeo
Format: Article
Language:English
Subjects:
Autoimmune Diseases - pathology
Biological and medical sciences
Biopsy
Cytoplasmic Granules - ultrastructure
Female
Gastroenterology. Liver. Pancreas. Abdomen
Hepatitis - pathology
Humans
Liver - pathology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Microscopy, Electron
Middle Aged
Other diseases. Semiology
Pseudopodia - ultrastructure
Vacuoles - ultrastructure
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This is the first report to document pit cells in the human liver. These cells were identified by characteristic electron‐dense granules and rod‐cored vesicles. The granules of human pit cells were smaller in number and size than those of the rat. In the present case of autoimmune hepatitis, pit cells and conventional agranular lymphocytes migrated into hepatic parenchyma and contacted degenerating and immature hepatocytes. Pit cells show natural killer activity (Kaneda et al., 1983), and may participate in development of lesions and cellular damage.
ISSN:0270-9139
1527-3350
DOI:10.1002/hep.1840040529