Combined intracoronary streptokinase and percutaneous coronary angioplasty for reperfusion of chronic total coronary occlusion

In a 40 year old man with a 1 month total occlusion of a dominant right coronary artery, persistent angina despite medical management indicated inadequate coronary collateral supply to the posterolateral myocardium originally supplied by the totally occluded vessel. Initial attempts at reperfusion o...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 1984-10, Vol.4 (4), p.820-824
Main Authors: Ferguson, David W., Kouba, Craig R., Little, Marta M., Osborne, James L., White, Carl W., Michael Kioschos, J.
Format: Article
Language:English
Subjects:
Adult
Angina Pectoris - drug therapy
Angina Pectoris - therapy
Angioplasty, Balloon
Biological and medical sciences
Cardiology. Vascular system
Combined Modality Therapy
Coronary Angiography
Coronary Disease - diagnostic imaging
Coronary Disease - drug therapy
Coronary Disease - physiopathology
Coronary Disease - therapy
Coronary heart disease
Coronary Vessels
Electrocardiography
Heart
Humans
Male
Medical sciences
Streptokinase - therapeutic use
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Summary:In a 40 year old man with a 1 month total occlusion of a dominant right coronary artery, persistent angina despite medical management indicated inadequate coronary collateral supply to the posterolateral myocardium originally supplied by the totally occluded vessel. Initial attempts at reperfusion of the chronically occluded vessel with an angioplasty guide wire and balloon were unsuc-cessful. However, administration of intracoronary streptokinase resulted in partial reperfusion, after which successful wire-guided balloon angioplasty was accomplished. This case illustrates the potential utility of combining a thrombolytic agent with angioplasty in attempting reperfusion for management of selected cases of chronic total coronary artery occlusion.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(84)80412-X