Adenosine Deaminase in Lymphocytes and its Electrophoretic Separation

The adenosine deaminase polymorphism was found in lymphocyte lysates. Lymphocytes exhibited an additional ADA isozyme distinguished from other ADA isozymes by its lack of free -SH groups. It was suggested that this new isozyme is controlled by a second genetic locus.

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Bibliographic Details
Published in:Human heredity 1971-01, Vol.21 (6), p.607-613
Main Author: Wüst, Hildegard
Format: Article
Language:English
Subjects:
Adenosine
Aminohydrolases - blood
Aminohydrolases - isolation & purification
Electrophoresis, Starch Gel
Erythrocytes - enzymology
Humans
Isoenzymes - isolation & purification
Lymphocytes - enzymology
Methods
Polymorphism, Genetic
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Description
Summary:The adenosine deaminase polymorphism was found in lymphocyte lysates. Lymphocytes exhibited an additional ADA isozyme distinguished from other ADA isozymes by its lack of free -SH groups. It was suggested that this new isozyme is controlled by a second genetic locus.
ISSN:0001-5652
1423-0062
DOI:10.1159/000152454