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THE MAIN HISTOCOMPATIBILITY COMPLEX AND AGEING IN MICE AND MEN
Studies of the relationship between the main histocompatibility complex and survival into old age are reviewed. In mice there is some evidence that the H2 system is involved with longevity. Studies in very old humans may help to explain the survival of genes modulating different immune responsivenes...
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Published in: | Age and ageing 1984-09, Vol.13 (5), p.291-294 |
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container_end_page | 294 |
container_issue | 5 |
container_start_page | 291 |
container_title | Age and ageing |
container_volume | 13 |
creator | Kafetz, K |
description | Studies of the relationship between the main histocompatibility complex and survival into old age are reviewed. In mice there is some evidence that the H2 system is involved with longevity. Studies in very old humans may help to explain the survival of genes modulating different immune responsiveness. |
doi_str_mv | 10.1093/ageing/13.5.291 |
format | article |
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Psychology</subject><subject>H-2 Antigens - immunology</subject><subject>Histocompatibility Antigens Class II - immunology</subject><subject>HLA Antigens - immunology</subject><subject>HLA-B8 Antigen</subject><subject>HLA-DR3 Antigen</subject><subject>Humans</subject><subject>Immune System - immunology</subject><subject>Major Histocompatibility Complex</subject><subject>Male</subject><subject>Mice - immunology</subject><subject>Molecular and cellular biology</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><recordid>eNo9kE1r20AQhpfSkDpuzz0VdCi9yd7ZT-kSUBzFUrHskqg09WXZXe8aJf5ItTYk_z5ybXwaZt5nhuFB6CvgAeCUDvXSNZvlEOiAD0gKH1APmEhiklD2EfUwxiTGkqSf0FUIT10LHMgluhQ0SYjkPXRdF3lUZeU0KsqHejaaVb-yurwpJ2X9Nzp0k_wxyqa3UTbOy-k46sCqHOX_R1U-_YwuvF4F9-VU--j3XV6PingyG5ejbBJbCnQXa-nFwhCjtZECqGCaMWcNJB6kFsYvDAMLiU1ZKoww0mHimZXMc2Cce0b76Mfx7ku7_bd3YafWTbButdIbt90HlQAlXHRC-mh4BG27DaF1Xr20zVq3bwqwOhhTR2MKqOKqM9ZtfDud3pu1W5z5k6Iu_37KdbB65Vu9sU04YykWUuLDh_ERa8LOvZ5j3T4rIankqnicK_Kzuk3_1PdqTt8BcFd9Xg</recordid><startdate>198409</startdate><enddate>198409</enddate><creator>Kafetz, K</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198409</creationdate><title>THE MAIN HISTOCOMPATIBILITY COMPLEX AND AGEING IN MICE AND MEN</title><author>Kafetz, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-a7f6db2baab761364a44ecb18f17a6bfdb41c18c9496b6b7e02f4c74f51455f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Ageing, cell death</topic><topic>Aging</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cell physiology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>H-2 Antigens - immunology</topic><topic>Histocompatibility Antigens Class II - immunology</topic><topic>HLA Antigens - immunology</topic><topic>HLA-B8 Antigen</topic><topic>HLA-DR3 Antigen</topic><topic>Humans</topic><topic>Immune System - immunology</topic><topic>Major Histocompatibility Complex</topic><topic>Male</topic><topic>Mice - immunology</topic><topic>Molecular and cellular biology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kafetz, K</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kafetz, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE MAIN HISTOCOMPATIBILITY COMPLEX AND AGEING IN MICE AND MEN</atitle><jtitle>Age and ageing</jtitle><addtitle>Age Ageing</addtitle><date>1984-09</date><risdate>1984</risdate><volume>13</volume><issue>5</issue><spage>291</spage><epage>294</epage><pages>291-294</pages><issn>0002-0729</issn><eissn>1468-2834</eissn><abstract>Studies of the relationship between the main histocompatibility complex and survival into old age are reviewed. In mice there is some evidence that the H2 system is involved with longevity. Studies in very old humans may help to explain the survival of genes modulating different immune responsiveness.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>6388275</pmid><doi>10.1093/ageing/13.5.291</doi><tpages>4</tpages></addata></record> |
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ispartof | Age and ageing, 1984-09, Vol.13 (5), p.291-294 |
issn | 0002-0729 1468-2834 |
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source | Oxford University Press:Jisc Collections:Oxford Journal Archive: Access period 2024-2025 |
subjects | Ageing, cell death Aging Animals Biological and medical sciences Cell physiology Female Fundamental and applied biological sciences. Psychology H-2 Antigens - immunology Histocompatibility Antigens Class II - immunology HLA Antigens - immunology HLA-B8 Antigen HLA-DR3 Antigen Humans Immune System - immunology Major Histocompatibility Complex Male Mice - immunology Molecular and cellular biology |
title | THE MAIN HISTOCOMPATIBILITY COMPLEX AND AGEING IN MICE AND MEN |
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