Pituitary craniopharyngioma with tooth formation

A classic pituitary craniopharyngioma was removed from the suprasellar and intrasellar regions of a 4‐year‐old boy. In each of 2 separate surgical specimens, a rudimentary tooth was found buried within the tumor. The implication of this finding in characterizing the embryology of the development of...

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Bibliographic Details
Published in:Cancer 1972-02, Vol.29 (2), p.423-430
Main Authors: Seemayer, T. A., Blundell, J. S., Wiglesworth, F. W.
Format: Article
Language:English
Subjects:
Ameloblastoma - embryology
Cell Differentiation
Child, Preschool
Craniopharyngioma - embryology
Craniopharyngioma - pathology
Humans
Jaw Neoplasms - embryology
Male
Odontogenesis
Pituitary Neoplasms - embryology
Pituitary Neoplasms - pathology
Tooth, Supernumerary - embryology
Tooth, Supernumerary - pathology
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Summary:A classic pituitary craniopharyngioma was removed from the suprasellar and intrasellar regions of a 4‐year‐old boy. In each of 2 separate surgical specimens, a rudimentary tooth was found buried within the tumor. The implication of this finding in characterizing the embryology of the development of the tooth and pituitary is discussed. It is concluded that this tumor arose from tissue which, by the production of a tooth, expressed its fullest capacity of differentiation, and that the craniopharyngioma is developmentally related to the adamantinoma of the jaw.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197202)29:2<423::AID-CNCR2820290225>3.0.CO;2-X