Family study in sickle Cell disease in Nigeria

A pilot survey has been made of Nigerian families at risk of producing SS haemoglobin homozygotes. Genotypes of parents and off-spring were investigated in twenty-five families. There is a suggestion that more SS children are produced where the first born suffers from haemoglobin SS disease. Mortali...

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Bibliographic Details
Published in:Journal of biosocial science 1972-07, Vol.4 (3), p.307-313
Main Authors: Lesi, F. E. A., Bassey, Ekpo E. E.
Format: Article
Language:English
Subjects:
Adolescent
Anemia, Sickle Cell - genetics
Anemia, Sickle Cell - mortality
Black/Blacks
Child
Child, Preschool
Female
Genotype
Humans
Infant
Male
Nigeria
Nigeria/Nigerian/Nigerians
Pilot Projects
Public health
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Summary:A pilot survey has been made of Nigerian families at risk of producing SS haemoglobin homozygotes. Genotypes of parents and off-spring were investigated in twenty-five families. There is a suggestion that more SS children are produced where the first born suffers from haemoglobin SS disease. Mortality among offspring was higher in the study population than in the general population.
ISSN:0021-9320
1469-7599
DOI:10.1017/S0021932000008622