Arthritis as the presenting feature of childhood leukemia

Five cases of childhood leukemia are described in which major presentation was arthritis. Three patients had normal hematologic studies when initially examined. Both monoarticular and polyarticular arthritis were seen. Joint swelling was caused by an increase in synovial fluid, but in 1 patient ther...

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Bibliographic Details
Published in:Arthritis and rheumatism 1972-07, Vol.15 (4), p.347-349
Main Authors: Fink, Chester W., Windmiller, Joan, Sartain, Peggy
Format: Article
Language:English
Subjects:
Adolescent
Arthritis - complications
Arthritis - diagnosis
Child
Child, Preschool
Diagnosis, Differential
Female
Humans
Leukemia - complications
Leukemia - diagnosis
Leukemia, Lymphoid - complications
Leukemia, Myeloid, Acute - complications
Leukocyte Count
Uric Acid - blood
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Summary:Five cases of childhood leukemia are described in which major presentation was arthritis. Three patients had normal hematologic studies when initially examined. Both monoarticular and polyarticular arthritis were seen. Joint swelling was caused by an increase in synovial fluid, but in 1 patient there seemed to be synovial thickening. Presentations and clinical courses were extremely variable and point out the necessity to consider leukemia in the differential diagnosis of children with arthritis.
ISSN:0004-3591
1529-0131
DOI:10.1002/art.1780150404