Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissues of rats performing swimming exercise

• Published in: Biological trace element research 2003-08, Vol.94 (2), p.157-166
• Main Authors: Ozturk, Ahmet, Baltaci, Abdulkerim Kasim, Mogulkoc, Rasim, Oztekin, Esma, Sivrikaya, Abdullah, Kurtoglu, Erdal, Kul, Aylin
• Format: Article
• Language: English
• Subjects: Animal tissues; Animals; Blood; Dietary Supplements; Erythrocytes - drug effects; Erythrocytes - metabolism; Exercise; Glutathione - analysis; Glutathione - blood; Kidney - drug effects; Kidney - metabolism; Kidneys; Liver - drug effects; Liver - metabolism; Male; Malondialdehyde - analysis; Malondialdehyde - blood; Muscles - drug effects; Muscles - metabolism; Peroxidation; Rats; Rats, Sprague-Dawley; Rodents; Swimming; Swimming - physiology; Testis - drug effects; Testis - metabolism; Tissues; Zinc; Zinc - administration & dosage; Zinc - deficiency; Zinc - pharmacology
• ISSN: 0163-4984; 0163-4984; 1559-0720
• DOI: 10.1385/bter:94:2:157

The aim of the study was to investigate the effects of zinc deficiency and supplementation on lipid peroxidation and glutathione levels in blood and in some tissues of rats performing swimming exercise. Forty adult male Sprague-Dawley rats were divided into four groups: group 1, zinc-deficient consisted of swimming rats; group 2 consisted of zinc-supplemented swimming rats; groups 3 and 4 were the swimming and nonswimming controls, respectively. The levels of malondialdehyde and glutathione were measured after 4 wk of zinc-deficient or zinc-supplemented diet and 30 min of swimming exercise daily. The erythrocyte glutathione levels of groups 2 and 4 were significantly higher than those of groups 1 and 3 (p