Quantitative Assessment of Neurons and Neuroglia with Computer Morphometry

The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm², numb...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2010-07, Vol.149 (1), p.100-103
Main Authors: Khudoerkov, R. M, Voronkov, D. N
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
brain
Cell Biology
Cell Count
Equipment and supplies
Glial Fibrillary Acidic Protein - metabolism
Guinea Pigs
image analysis
Image processing
Image Processing, Computer-Assisted
Immunoenzyme Techniques
Internal Medicine
Laboratory Medicine
morphometry
neuroglia
Neuroglia - cytology
neuron
Neurons
Neurons - cytology
Pathology
Photomicrography
Rats
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Summary:The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm², number of satellite perineuronal glial cells, aspect ratio for neural and glial cells, the area occupied by neuroglial projections, etc. The tested computer morphometry methods can be efficient in quantitative assessment of pathological and regenerative processes in the nervous tissue.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-010-0886-3