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Use of 4,4′-Dinitrostilbene-2,2′-Disulfonic Acid Wastewater As a Raw Material for Paramycin Production

This study uses 4,4′-dinitrostilbene-2,2′-disulfonic acid (DNS) wastewater to produce paramycin (4-amino-2-hydroxybenzoic acid), an antitubercular agent and important pharmaceutical intermediate. The high concentrations of aromatic sulfonic acids contained in the wastewater, derived from a DNS produ...

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Published in:Environmental science & technology 2010-12, Vol.44 (23), p.9157-9162
Main Authors: Peng, Wenchao, Chen, Ying, Fan, Shidong, Zhang, Fengbao, Zhang, Guoliang, Fan, Xiaobin
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Language:English
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cited_by cdi_FETCH-LOGICAL-a437t-7f710959e49e73f3c2f3af6f81001c0bd3eb01919add9e3de5417f772c1c2b973
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container_issue 23
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container_title Environmental science & technology
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creator Peng, Wenchao
Chen, Ying
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description This study uses 4,4′-dinitrostilbene-2,2′-disulfonic acid (DNS) wastewater to produce paramycin (4-amino-2-hydroxybenzoic acid), an antitubercular agent and important pharmaceutical intermediate. The high concentrations of aromatic sulfonic acids contained in the wastewater, derived from a DNS production facility, have been transformed to paramycin in yields of more than 85%. This waste-disposal strategy, which combines oxidation using NaClO, reduction using iron powder, and subsequent alkaline fusion with NaOH, has been proven to be successful in dealing with ton-scale DNS wastewater. Compared with common treatment methods, which usually involve degrading the compounds, this new method recycles most of the aromatic sulfonic acids in the wastewater to produce paramycin. This effectively solves the associated environment problems associated with DNS wastewater and is also potentially profitable. The present approach could also lead to alternative solutions for dealing with other industrial wastewaters generated from oxidative coupling reactions of nitro-substituted toluenes to the corresponding substituted stilbenes.
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Aminosalicylic Acid - chemical synthesis
Antibiotics
Antitubercular Agents - chemical synthesis
Applied sciences
Comparative analysis
Exact sciences and technology
Oxidation
Oxidation-Reduction
Pollution
Profitability
Stilbenes - analysis
Stilbenes - chemistry
Studies
Sustainability Engineering and Green Chemistry
Waste disposal
Waste Disposal, Fluid - methods
Water Pollutants, Chemical - analysis
Water Pollutants, Chemical - chemistry
Water reuse
title Use of 4,4′-Dinitrostilbene-2,2′-Disulfonic Acid Wastewater As a Raw Material for Paramycin Production
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