Risk Factors for Venous Thromboembolism in Patients with Human Immunodeficiency Virus Infection

• Published in: Pharmacotherapy 2010-12, Vol.30 (12), p.1292-1302
• Main Authors: Kiser, Katie L., Badowski, Melissa E.
• Format: Article
• Language: English
• Subjects: acquired immunodeficiency syndrome; Age Factors; AIDS; AIDS-Related Opportunistic Infections - complications; Antiphospholipid Syndrome - complications; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; CD4+ count; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Hematologic and hematopoietic diseases; HIV; HIV Infections - complications; human immunodeficiency virus; Human viral diseases; Humans; Immunosuppression - adverse effects; Infectious diseases; Medical sciences; Models, Biological; opportunistic infections; Opportunistic Infections - complications; Pharmacology. Drug treatments; Platelet diseases and coagulopathies; Protease Inhibitors; protein C deficiency; Protein C Deficiency - complications; protein S deficiency; Protein S Deficiency - complications; Risk Factors; Sex Factors; venous thromboembolism; Venous Thromboembolism - complications; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; viral load
• ISSN: 0277-0008; 1875-9114
• DOI: 10.1592/phco.30.12.1292

Prevention and treatment of venous thromboembolism are gaining attention in the lay and medical communities because of an increase in frequency, cost, and risk factors. Evidence shows that patients with human immunodeficiency virus (HIV) have multiple risk factors and a 2–10‐fold increased risk for venous thromboembolism compared with the general population. A higher rate of venous thromboembolism also occurs in patients with HIV who are younger than 50 years (3.31% vs 0.53% in age‐matched healthy controls, p