Localized expression pattern of miR-184 in Drosophila

MicroRNAs (miRNAs) are a kind of endogenous non-coding small RNAs whose specific functions in animals are generally important. Although functions of some miRNAs have been identified, the role of miR-184 remains unknown. Here, we determined the temporal and spatial expression pattern of miR-184 durin...

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Bibliographic Details
Published in:Molecular biology reports 2011-01, Vol.38 (1), p.355-358
Main Authors: Li, Ping, Peng, Jianjian, Hu, Jiangbo, Xu, Zhongxin, Xie, Wei, Yuan, Liudi
Format: Article
Language:English
Subjects:
Animal Anatomy
Animal Biochemistry
Animals
Base Sequence
Biomedical and Life Sciences
Drosophila
Drosophila melanogaster - genetics
Drosophila melanogaster - growth & development
Embryo, Nonmammalian - metabolism
Embryonic Development - genetics
Expression pattern
Female
Gene expression
Gene Expression Profiling
Gene Expression Regulation, Developmental
Genetic Loci - genetics
Histology
Insects
Larva - genetics
Life Sciences
Male
MicroRNAs - genetics
MicroRNAs - metabolism
miR-184
Molecular Sequence Data
Morphology
Physical Chromosome Mapping
RNA, Messenger - genetics
RNA, Messenger - metabolism
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Summary:MicroRNAs (miRNAs) are a kind of endogenous non-coding small RNAs whose specific functions in animals are generally important. Although functions of some miRNAs have been identified, the role of miR-184 remains unknown. Here, we determined the temporal and spatial expression pattern of miR-184 during the different development stages and tissues in Drosophila. Strikingly, miR-184 is expressed ubiquitously in Drosophila embryos, larvae and adults, its expression pattern shows a dynamic changes during the development of embryo, especially in the central nervous system. This expression profile suggests that miR-184 may act important function in Drosophila development.
ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-010-0115-1